Structure of PDB 5kro Chain A Binding Site BS01
Receptor Information
>5kro Chain A (length=229) Species:
9606
(Homo sapiens) [
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LALSLTADQMVSALLDAEPPILYSEYRPFSEASMMGLLTNLADRELVHMI
NWAKRVPGFVDLTLHDQVHLLECAWLEILMIGLVWRSMEHPGKLLFAPNL
LLDRNQGKCVEGMVEIFDMLLATSSRFRMMNLQGEEFVCLKSIILLNSGV
YTKDHIHRVLDKITDTLIHLMAKAGLTLQQQHQRLAQLLLILSHIRHMSN
KGMEHLYSMKCKNVVPLSDLLLEMLDAHR
Ligand information
>5kro Chain C (length=9) Species:
9606
(Homo sapiens) [
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KILHRLLQD
Receptor-Ligand Complex Structure
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PDB
5kro
Systems Structural Biology Analysis of Ligand Effects on ER alpha Predicts Cellular Response to Environmental Estrogens and Anti-hormone Therapies.
Resolution
2.1 Å
Binding residue
(original residue number in PDB)
I358 K362 V376 L379 E380 D538 L539 E542
Binding residue
(residue number reindexed from 1)
I50 K54 V68 L71 E72 D219 L220 E223
Enzymatic activity
Enzyme Commision number
?
External links
PDB
RCSB:5kro
,
PDBe:5kro
,
PDBj:5kro
PDBsum
5kro
PubMed
28042045
UniProt
P03372
|ESR1_HUMAN Estrogen receptor (Gene Name=ESR1)
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