Structure of PDB 5krk Chain A Binding Site BS01
Receptor Information
>5krk Chain A (length=228) Species:
9606
(Homo sapiens) [
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SLALSLTADQMVSALLDAEPPILYSEYPFSEASMMGLLTNLADRELVHMI
NWAKRVPGFVDLTLHDQVHLLECAWLEILMIGLVWRSMEHPGKLLFAPNL
LLDRNQGKCVEGMVEIFDMLLATSSRFRMMNLQGEEFVCLKSIILLNSGV
YTKDHIHRVLDKITDTLIHLMAKAGLTLQQQHQRLAQLLLILSHIRHMSN
KGMEHLYSMKCKNVPLSDLLLEMLDAHR
Ligand information
>5krk Chain C (length=10) Species:
9606
(Homo sapiens) [
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HKILHRLLQD
Receptor-Ligand Complex Structure
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PDB
5krk
Systems Structural Biology Analysis of Ligand Effects on ER alpha Predicts Cellular Response to Environmental Estrogens and Anti-hormone Therapies.
Resolution
2.391 Å
Binding residue
(original residue number in PDB)
I358 K362 V376 L379 D538 E542
Binding residue
(residue number reindexed from 1)
I50 K54 V68 L71 D218 E222
Enzymatic activity
Enzyme Commision number
?
External links
PDB
RCSB:5krk
,
PDBe:5krk
,
PDBj:5krk
PDBsum
5krk
PubMed
28042045
UniProt
P03372
|ESR1_HUMAN Estrogen receptor (Gene Name=ESR1)
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