Structure of PDB 5krf Chain A Binding Site BS01
Receptor Information
>5krf Chain A (length=234) Species:
9606
(Homo sapiens) [
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NSLALSLTADQMVSALLDAEPPILYSEYDPTRPFSEASMMGLLTNLADRE
LVHMINWAKRVPGFVDLTLHDQVHLLECAWLEILMIGLVWRSMEHPGKLL
FAPNLLLDRNQGKCVEGMVEIFDMLLATSSRFRMMNLQGEEFVCLKSIIL
LNSGVYTKDHIHRVLDKITDTLIHLMAKAGLTLQQQHQRLAQLLLILSHI
RHMSNKGMEHLYSMKCKNVVPLSDLLLEMLDAHR
Ligand information
>5krf Chain C (length=10) Species:
32630
(synthetic construct) [
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HKILHRLLQD
Receptor-Ligand Complex Structure
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PDB
5krf
Systems Structural Biology Analysis of Ligand Effects on ER alpha Predicts Cellular Response to Environmental Estrogens and Anti-hormone Therapies.
Resolution
2.193 Å
Binding residue
(original residue number in PDB)
I358 K362 L372 V376 E380 E542
Binding residue
(residue number reindexed from 1)
I55 K59 L69 V73 E77 E228
Enzymatic activity
Enzyme Commision number
?
External links
PDB
RCSB:5krf
,
PDBe:5krf
,
PDBj:5krf
PDBsum
5krf
PubMed
28042045
UniProt
P03372
|ESR1_HUMAN Estrogen receptor (Gene Name=ESR1)
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