Structure of PDB 5kra Chain A Binding Site BS01
Receptor Information
>5kra Chain A (length=226) Species:
9606
(Homo sapiens) [
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SLALSLTADQMVSALLDAEPPILYSEYFSEASMMGLLTNLADRELVHMIN
WAKRVPGFVDLTLHDQVHLLECAWLEILMIGLVWRSMEHPGKLLFAPNLL
LDRNQVEGMVEIFDMLLATSSRFRMMNLQGEEFVCLKSIILLNSGVYTFK
DHIHRVLDKITDTLIHLMAKAGLTLQQQHQRLAQLLLILSHIRHMSNKGM
EHLYSMKCKNVVPLSDLLLEMLDAHR
Ligand information
>5kra Chain C (length=10) Species:
9606
(Homo sapiens) [
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HKILHRLLQD
Receptor-Ligand Complex Structure
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PDB
5kra
Systems Structural Biology Analysis of Ligand Effects on ER alpha Predicts Cellular Response to Environmental Estrogens and Anti-hormone Therapies.
Resolution
2.401 Å
Binding residue
(original residue number in PDB)
I358 K362 L372 V376 E380 D538 L539 E542
Binding residue
(residue number reindexed from 1)
I49 K53 L63 V67 E71 D216 L217 E220
Enzymatic activity
Enzyme Commision number
?
External links
PDB
RCSB:5kra
,
PDBe:5kra
,
PDBj:5kra
PDBsum
5kra
PubMed
28042045
UniProt
P03372
|ESR1_HUMAN Estrogen receptor (Gene Name=ESR1)
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