Structure of PDB 5kr9 Chain A Binding Site BS01
Receptor Information
>5kr9 Chain A (length=236) Species:
9606
(Homo sapiens) [
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NSLALSLTADQMVSALLDAEPPILYSEYDPTRPFSEASMMGLLTNLADRE
LVHMINWAKRVPGFVDLTLHDQVHLLECAWLEILMIGLVWRSMEHPGKLL
FAPNLLLDRNQGKCVEGMVEIFDMLLATSSRFRMMNLQGEEFVCLKSIIL
LNSGVYTFKDHIHRVLDKITDTLIHLMAKAGLTLQQQHQRLAQLLLILSH
IRHMSNKGMEHLYSMKCKNVVPLSDLLLEMLDAHRL
Ligand information
>5kr9 Chain C (length=12) Species:
9606
(Homo sapiens) [
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HKILHRLLQDSS
Receptor-Ligand Complex Structure
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PDB
5kr9
Systems Structural Biology Analysis of Ligand Effects on ER alpha Predicts Cellular Response to Environmental Estrogens and Anti-hormone Therapies.
Resolution
2.25 Å
Binding residue
(original residue number in PDB)
I358 N359 K362 R363 L372 V376 E380 D538 L539 E542
Binding residue
(residue number reindexed from 1)
I55 N56 K59 R60 L69 V73 E77 D225 L226 E229
Enzymatic activity
Enzyme Commision number
?
External links
PDB
RCSB:5kr9
,
PDBe:5kr9
,
PDBj:5kr9
PDBsum
5kr9
PubMed
28042045
UniProt
P03372
|ESR1_HUMAN Estrogen receptor (Gene Name=ESR1)
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