Structure of PDB 5kkl Chain A Binding Site BS01

Receptor Information
>5kkl Chain A (length=481) Species: 759272 (Thermochaetoides thermophila DSM 1495) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
DSAEWELPRLRTSFIFQDDYKYLDLAEFFDVKFYPYSPPGAPPVFAATSK
KHAVICRLTQTTDKDANPCEIIQLIRDDGNEANCASCWSKDPITDQPLLC
IAGNEGNVKVYNVTEGKLYRTLVGHGGGINDLATSPANPYIIASASDDTT
IRIWSLAPEHEKQPCVCILGGEGHSYDLLSVAFHDNGRYVLSAGHDQVIN
LWALPEFPNEHMEIPIVIYYPHFSSSEIHNNLVDCVAFYGDLILSRACHE
DTIVLWRIEGFSSDDPIPGPLDAPTPTDMTKQTRSYFTPTVSPQSRPAMF
TRLAQFHTPDCGVQFFMRFRMYHVPGKHPILAFANAKSKTFFWDLARFGE
YARFMADLKEAQQSYNGRVVVVDQGISLAQAQQVHGPGVGVVMKPAWLVP
KMVSASPDPDSPFGFSRETLQAWADMYDLSNPVGLIKAHRSLAIDGAFVG
RQVGWSPEGEWCVVVGNGNRALIYQRWGKER
Ligand information
Receptor-Ligand Complex Structure
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PDB5kkl Response to Comment on "Structural basis of histone H3K27 trimethylation by an active polycomb repressive complex 2".
Resolution2.94 Å
Binding residue
(original residue number in PDB)		V325 Q326 F327 F328 R526 N542
Binding residue
(residue number reindexed from 1)		V313 Q314 F315 F316 R451 N467
Enzymatic activity
Enzyme Commision number ?
Gene Ontology
Molecular Function
GO:0031491 nucleosome binding
Biological Process
GO:0000122 negative regulation of transcription by RNA polymerase II
GO:0006325 chromatin organization
Cellular Component
GO:0005634 nucleus

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Molecular Function
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Biological Process
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Cellular Component
External links
PDB RCSB:5kkl, PDBe:5kkl, PDBj:5kkl
PDBsum5kkl
PubMed28008038
UniProtG0S8H7

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