Structure of PDB 5kiv Chain A Binding Site BS01

Receptor Information
>5kiv Chain A (length=262) Species: 1280 (Staphylococcus aureus) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
GSHMASMETLKSNKARLEYLINDMRRERMPSSFEDLWELYRGLANVRPAL
PVSDEYLAVQDAMLSDLNHQHVTDLKDLKPIKGDNIFVWQGDITTLKIDA
IVNAANSRFLGCMQANHDCIDNIIHTKAGVQVRLDCAEIIRQQGRNEGVG
KAKKTRGYNLPAKYIIHTVGPQIRRLPVSKMNQDLLAKCYLSCLKLADQH
SLNHVAFCCISTGVFAFPQDEAAEIAVRTVESYLKETNSTLKVVFNVFTD
KDLQLYKEALNR
Ligand information
Ligand IDZN
InChIInChI=1S/Zn/q+2
InChIKeyPTFCDOFLOPIGGS-UHFFFAOYSA-N
SMILES
SoftwareSMILES
CACTVS 3.341[Zn++]
ACDLabs 10.04
OpenEye OEToolkits 1.5.0		[Zn+2]
FormulaZn
NameZINC ION
ChEMBLCHEMBL1236970
DrugBankDB14532
ZINC
PDB chain5kiv Chain A Residue 301 [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
Receptor-Ligand Complex Structure
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PDB5kiv Structure of the sirtuin-linked macrodomain SAV0325 from Staphylococcus aureus.
Resolution1.75 Å
Binding residue
(original residue number in PDB)		C113 H118 C120
Binding residue
(residue number reindexed from 1)		C112 H117 C119
Annotation score1
Enzymatic activity
Enzyme Commision number 3.2.1.-
Gene Ontology
Molecular Function
GO:0016798 hydrolase activity, acting on glycosyl bonds

View graph for
Molecular Function
External links
PDB RCSB:5kiv, PDBe:5kiv, PDBj:5kiv
PDBsum5kiv
PubMed27345688
UniProtP67344|ADPRH_STAAN Protein-ADP-ribose hydrolase (Gene Name=SA0314)

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