Structure of PDB 5ke6 Chain A Binding Site BS01

Receptor Information
>5ke6 Chain A (length=85) Species: 10090 (Mus musculus) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
THTCDYAGCGKTYTKSSHLKAHLRTHTGEKPYHCDWDGCGWKFARSDELT
RHYRKHTGHRPFQCQKCDRAFSRSDHLALHMKRHF
Ligand information
Receptor-Ligand Complex Structure
Global viewLocal viewStructure summary

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PDB5ke6 Distinctive Klf4 mutants determine preference for DNA methylation status.
Resolution1.99 Å
Binding residue
(original residue number in PDB)
Y411 H416 R443 E446 R449 R471 H474
Binding residue
(residue number reindexed from 1)
Y13 H18 R45 E48 R51 R73 H76
Binding affinityPDBbind-CN: Kd=0.19uM
Enzymatic activity
Enzyme Commision number ?
External links
PDB RCSB:5ke6, PDBe:5ke6, PDBj:5ke6
PDBsum5ke6
PubMed27596594
UniProtQ60793|KLF4_MOUSE Krueppel-like factor 4 (Gene Name=Klf4)

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