Structure of PDB 5kcu Chain A Binding Site BS01
Receptor Information
>5kcu Chain A (length=226) Species:
9606
(Homo sapiens) [
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LALSLTADQMVSALLDAEPPILYSEYPFSEASMMGLLTNLADRELVHMIN
WAKRVPGFVDLTLHDQVHLLECAWLEILMIGLVWRSMEHPGKLLFAPNLL
LDRNQGKCVEGMVEIFDMLLATSSRFRMMNLQGEEFVCLKSIILLNSGVY
TFKDHIHRVLDKITDTLIHLMAKAGLTLQQQHQRLAQLLLILSHIRHMSN
KGMEHLYSMKCKNLSDLLLEMLDAHR
Ligand information
>5kcu Chain C (length=10) Species:
9606
(Homo sapiens) [
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HKILHRLLQD
Receptor-Ligand Complex Structure
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PDB
5kcu
Full antagonism of the estrogen receptor without a prototypical ligand side chain.
Resolution
2.03 Å
Binding residue
(original residue number in PDB)
I358 K362 L372 V376 E380 L539 E542
Binding residue
(residue number reindexed from 1)
I49 K53 L63 V67 E71 L217 E220
Enzymatic activity
Enzyme Commision number
?
External links
PDB
RCSB:5kcu
,
PDBe:5kcu
,
PDBj:5kcu
PDBsum
5kcu
PubMed
27870835
UniProt
P03372
|ESR1_HUMAN Estrogen receptor (Gene Name=ESR1)
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