Structure of PDB 5kce Chain A Binding Site BS01
Receptor Information
>5kce Chain A (length=223) Species:
9606
(Homo sapiens) [
Search protein sequence
] [
Download receptor structure
] [
Download structure with residue number starting from 1
] [
View receptor structure
]
KNSLALSLTADQMVSALLDAEPPILYSEYSMMGLLTNLADRELVHMINWA
KRVPGFVDLTLHDQVHLLECAWLEILMIGLVWRSMEHPGKLLFAPNLLLD
RNQGKCVEGMVEIFDMLLATSSRFRMMNLQGEEFVCLKSIILLNSGDHIH
RVLDKITDTLIHLMAKAGLTLQQQHQRLAQLLLILSHIRHMSNKGMEHLY
SMKCKNVVPLSDLLLEMLDAHRL
Ligand information
>5kce Chain D (length=8) Species:
9606
(Homo sapiens) [
Search peptide sequence
] [
Download ligand structure
] [
Download structure with residue number starting from 1
] [
View ligand structure
]
KILHRLLQ
Receptor-Ligand Complex Structure
Global view
Local view
Structure summary
[
Spin on
] [
Spin off
] [
Reset
]
[
High quality
] [
Low quality
]
[
White background
] [
Black background
]
[
Spin on
] [
Spin off
] [
Reset
]
[
High quality
] [
Low quality
]
[
White background
] [
Black background
]
PDB
5kce
Full antagonism of the estrogen receptor without a prototypical ligand side chain.
Resolution
1.847 Å
Binding residue
(original residue number in PDB)
I358 K362 L539 E542 M543
Binding residue
(residue number reindexed from 1)
I47 K51 L213 E216 M217
Enzymatic activity
Enzyme Commision number
?
External links
PDB
RCSB:5kce
,
PDBe:5kce
,
PDBj:5kce
PDBsum
5kce
PubMed
27870835
UniProt
P03372
|ESR1_HUMAN Estrogen receptor (Gene Name=ESR1)
[
Back to BioLiP
]
