Structure of PDB 5kcc Chain A Binding Site BS01
Receptor Information
>5kcc Chain A (length=237) Species:
9606
(Homo sapiens) [
Search protein sequence
] [
Download receptor structure
] [
Download structure with residue number starting from 1
] [
View receptor structure
]
SLALSLTADQMVSALLDAEPPILYSEYDPTRPFSEASMMGLLTNLADREL
VHMINWAKRVPGFVDLTLHDQVHLLECAWLEILMIGLVWRSMEHPGKLLF
APNLLLDRNQGKCVEGMVEIFDMLLATSSRFRMMNLQGEEFVCLKSIILL
NSGVYTSLEEKDHIHRVLDKITDTLIHLMAKAGLTLQQQHQRLAQLLLIL
SHIRHMSNKGMEHLYSMKCKNVVPLSDLLLEMLDAHR
Ligand information
>5kcc Chain C (length=10) Species:
9606
(Homo sapiens) [
Search peptide sequence
] [
Download ligand structure
] [
Download structure with residue number starting from 1
] [
View ligand structure
]
KILHRLLQDS
Receptor-Ligand Complex Structure
Global view
Local view
Structure summary
[
Spin on
] [
Spin off
] [
Reset
]
[
High quality
] [
Low quality
]
[
White background
] [
Black background
]
[
Spin on
] [
Spin off
] [
Reset
]
[
High quality
] [
Low quality
]
[
White background
] [
Black background
]
PDB
5kcc
Full antagonism of the estrogen receptor without a prototypical ligand side chain.
Resolution
2.386 Å
Binding residue
(original residue number in PDB)
I358 K362 L372 V376 L379 D538 L539 E542
Binding residue
(residue number reindexed from 1)
I54 K58 L68 V72 L75 D227 L228 E231
Enzymatic activity
Enzyme Commision number
?
External links
PDB
RCSB:5kcc
,
PDBe:5kcc
,
PDBj:5kcc
PDBsum
5kcc
PubMed
27870835
UniProt
P03372
|ESR1_HUMAN Estrogen receptor (Gene Name=ESR1)
[
Back to BioLiP
]
