Structure of PDB 5kca Chain A Binding Site BS01

Receptor Information
>5kca Chain A (length=807) Species: 9606 (Homo sapiens) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
SAKVAFSAIRSTNHEPSEMSNRTMIIYFDQVLVNIGNNFDSERSTFIAPR
KGIYSFNFHVVKVYNRQTIQVSLMLNGWPVISAFAGDQDVTREAASNGVL
IQMEKGDRAYLKLERGNLMGGWKYSTFSGFLVFPLSAKVAFSAIRSTNHE
PSEMSNRTMIIYFDQVLVNIGNNFDSERSTFIAPRKGIYSFNFHVVKVYN
RQTIQVSLMLNGWPVISAFAGDQDVTREAASNGVLIQMEKGDRAYLKLER
GNLMGGWKYSTFSGFLVFPLGSSGSAKVAFSAIRSTNHEPSEMTMIIYFD
QVLVNIGNNFDSERSTFIAPRKGIYSFNFHVVKVYNRQTIQVSLMLNGWP
VISAFAGDQDVTREAASNGVLIQMEKGDRAYLKLERGNLMGGWKYSTFSG
FLVFPLSDSIIHIGAIFDESAKKDDEVFRTAVGDLNQNEEILQTEKITFS
VTFVDGNNPFQAVQEACELMNQGILALVSSIGCTSAGSLQSLADAMHIPH
LFIQRSTAGTPRSGCGLTRSNRNDDYTLSVRPPVYLHDVILRVVTEYAWQ
KFIIFYDSEYDIRGIQEFLDKVSQQGMDVALQKVENNINKMITTLFDTMR
IEELNRYRDTLRRAILVMNPATAKSFITEVVETNLVAFDCHWIIINEEIN
DVDVQELVRRSIGRLTIIRQTFPVPQNISQRCFRGNHRISSTLCDPKDPF
AQNMEISNLYIYDTVLLLANAFHKKLEDRKWHSMASLSCIRKNSKPWQGG
RSMLETIKKGGVSGLTGELEFGENGGNPNVHFEILGTNYGGVRKLGCWNP
VTGLNGS
Ligand information
Ligand IDCA
InChIInChI=1S/Ca/q+2
InChIKeyBHPQYMZQTOCNFJ-UHFFFAOYSA-N
SMILES
SoftwareSMILES
CACTVS 3.341[Ca++]
ACDLabs 10.04
OpenEye OEToolkits 1.5.0		[Ca+2]
FormulaCa
NameCALCIUM ION
ChEMBL
DrugBankDB14577
ZINC
PDB chain5kca Chain A Residue 1001 [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
Receptor-Ligand Complex Structure
Global viewLocal viewStructure summary

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PDB5kca Structural basis for integration of GluD receptors within synaptic organizer complexes.
Resolution3.1 Å
Binding residue
(original residue number in PDB)		V760 R761 S763 Y891
Binding residue
(residue number reindexed from 1)		V658 R659 S661 Y789
Annotation score4
Enzymatic activity
Enzyme Commision number ?
External links
PDB RCSB:5kca, PDBe:5kca, PDBj:5kca
PDBsum5kca
PubMed27418511
UniProtO43424|GRID2_HUMAN Glutamate receptor ionotropic, delta-2 (Gene Name=GRID2);
P23435

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