Structure of PDB 5kal Chain A Binding Site BS01

Receptor Information
>5kal Chain A (length=325) Species: 5691 (Trypanosoma brucei) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
PPSPAVVGRSLVNSFKQFVSHVDATYRLVLDCVAAVDPLMRLYTFGSTVV
YGVHEKGSDVDFVVLNKTDVEDGKGGDAATQVAKGLQADILAKLARVIRQ
KHLSWNVEEVRRTRVPVVRVKGGGAVDFDITAYRRNGVRNSALLRAYFEQ
NPPCRWLSMSIKRWSKQTGLNASVIGGSITSYGFNLMVVYYLLQRNHLQF
VPPSTIDVSRVEPLPPHLPLEEPADEGLELGTQVLDFLHFFLHEFDSDKQ
VISLNRPGITTKEELDWTKSAEDFARMNGEKVHYQWCIEDPYELNLNVGR
NVTPLKRDFLRRHLEKARDTALLTI
Ligand information
Receptor-Ligand Complex Structure
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PDB5kal RNA Editing TUTase 1: structural foundation of substrate recognition, complex interactions and drug targeting.
Resolution2.75 Å
Binding residue
(original residue number in PDB)		D68 V117
Binding residue
(residue number reindexed from 1)		D61 V110
Enzymatic activity
Enzyme Commision number 2.7.7.52: RNA uridylyltransferase.
Gene Ontology
Molecular Function
GO:0000166 nucleotide binding
GO:0003723 RNA binding
GO:0016779 nucleotidyltransferase activity
GO:0046872 metal ion binding
GO:0050265 RNA uridylyltransferase activity
Biological Process
GO:0071076 RNA 3' uridylation
Cellular Component
GO:0005737 cytoplasm
GO:0005739 mitochondrion
GO:0020023 kinetoplast

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Molecular Function
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Biological Process
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Cellular Component
External links
PDB RCSB:5kal, PDBe:5kal, PDBj:5kal
PDBsum5kal
PubMed27744351
UniProtQ381M1|TUT4_TRYB2 Terminal uridylyltransferase 4 (Gene Name=TUT4)

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