Structure of PDB 5k6s Chain A Binding Site BS01

Receptor Information
>5k6s Chain A (length=323) Species: 9606 (Homo sapiens) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
DQEKLFIQKLRQCCVLFDFVSDPLSDLKWKEVKRAALSEMVEYITHNRNV
ITEPIYPEVVHMFAVNMFRTLPPEAAWPHLQLVYEFFLRFLESPDFQPNI
AKKYIDQKFVLQLLELFDSEDPRERDFLKTTLHRIYGKFLGLRAYIRKQI
NNIFYRFIYETEHHNGIAELLEILGSIINGFALPLKEEHKIFLLKVLLPL
HKVKSLSVYHPQLAYCVVQFLEKDSTLTEPVVMALLKYWPKTHSPKEVMF
LNELEEILDVIEPSEFVKIMEPLFRQLAKCVSSPHFQVAERALYYWNNEY
IMSLISDNAAKILPIMFPSLYRN
Ligand information
Receptor-Ligand Complex Structure
Global viewLocal viewStructure summary

[Spin on] [Spin off] [Reset]
[High quality] [Low quality]
[White background] [Black background]

[Spin on] [Spin off] [Reset]
[High quality] [Low quality]
[White background] [Black background]
PDB5k6s Expanding the PP2A Interactome by Defining a B56-Specific SLiM.
Resolution2.794 Å
Binding residue
(original residue number in PDB)
H187 R188 Y190 L194 R197 S230 N233 G234 F235 A236
Binding residue
(residue number reindexed from 1)
H133 R134 Y136 L140 R143 S176 N179 G180 F181 A182
Enzymatic activity
Enzyme Commision number ?
Gene Ontology
Molecular Function
GO:0019888 protein phosphatase regulator activity
Biological Process
GO:0007165 signal transduction
Cellular Component
GO:0000159 protein phosphatase type 2A complex

View graph for
Molecular Function

View graph for
Biological Process

View graph for
Cellular Component
External links
PDB RCSB:5k6s, PDBe:5k6s, PDBj:5k6s
PDBsum5k6s
PubMed27998540
UniProtQ13362|2A5G_HUMAN Serine/threonine-protein phosphatase 2A 56 kDa regulatory subunit gamma isoform (Gene Name=PPP2R5C)

[Back to BioLiP]