Structure of PDB 5jxp Chain A Binding Site BS01

Receptor Information
>5jxp Chain A (length=662) Species: 553175 (Porphyromonas endodontalis ATCC 35406) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
MDGGMWLMQQINGQVARMKSLGMQLEAADIYNPNGSSLKDAVVMFDGGCT
GVLVSNQGLLLTNHHCGYDQIQKHSSVQHNYLKDGFWSYSLAEELVNPGL
EVEIVDEITDVTAAVKKELERIKKPSGLEFLSPRYLSSLAPEIVASRPGY
RYEIKAFYGGNRYYMFTKKVFRDVRLVAAPPSSIGKFGSDTDNWAWPRHT
GDFSIFRLYADKNGNPAEYSKDNVPYRPKRWVKVNAQGVKEGDFALIMGY
PGTTYKFFTADEVTEWSEIDNNIRIEMRGILQDVMLREMLRRSLREIKLA
QQQEVLAWAKQKGIATTEEAVRAISKAIEGRQDLRMRQRYLLEGILMGIE
MSNAPAADSDIADHWDDPARREAGLQSIRKQFEAFFNKDYSPEVEKDQLA
IALLTRYAERIPAEKQPISIREGIAEYGSAKAYVEMIFDKSIYASRERFE
EFMKNPDRDRLLRDPMSRFAASVAYEHQKLAKEVAAFDAPLAAAQRSYVA
SVLDMKGQPNLAPDANLTLRFTYGEIKGYQPRDVVTYGAKSTLEGVMEKE
DPNNWEYVVDPKLKALYEAKNYGRYANSDGSMPVNFCATTHTTGGNAGSP
VMNARGELIGLNFDRNWEGVGGDIEYLPNYQRSIILDIRYLLFIIDKFAG
CQRLIDEIQPQF
Ligand information
Ligand IDCA
InChIInChI=1S/Ca/q+2
InChIKeyBHPQYMZQTOCNFJ-UHFFFAOYSA-N
SMILES
SoftwareSMILES
CACTVS 3.341[Ca++]
ACDLabs 10.04
OpenEye OEToolkits 1.5.0		[Ca+2]
FormulaCa
NameCALCIUM ION
ChEMBL
DrugBankDB14577
ZINC
PDB chain5jxp Chain A Residue 801 [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
Receptor-Ligand Complex Structure
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PDB5jxp Bacterial protease uses distinct thermodynamic signatures for substrate recognition.
Resolution2.5 Å
Binding residue
(original residue number in PDB)		N632 S633
Binding residue
(residue number reindexed from 1)		N577 S578
Annotation score4
Enzymatic activity
Enzyme Commision number 3.4.14.-
Gene Ontology
Molecular Function
GO:0004177 aminopeptidase activity
GO:0008236 serine-type peptidase activity
GO:0008239 dipeptidyl-peptidase activity
GO:0070009 serine-type aminopeptidase activity
Biological Process
GO:0006508 proteolysis
GO:0043171 peptide catabolic process
Cellular Component
GO:0005576 extracellular region
GO:0009986 cell surface

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Molecular Function
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Biological Process
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Cellular Component
External links
PDB RCSB:5jxp, PDBe:5jxp, PDBj:5jxp
PDBsum5jxp
PubMed28588213
UniProtF8WQK8|DPP11_POREA Asp/Glu-specific dipeptidyl-peptidase (Gene Name=dpp11)

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