Structure of PDB 5jne Chain A Binding Site BS01

Receptor Information
>5jne Chain A (length=351) Species: 559292 (Saccharomyces cerevisiae S288C) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
PTIHFKESPFYKIQRLIPELVMNVEVTGGRGMCSAKFKLSKADYNLLSNP
NSKHRLYLFSGMINPLGSRGNEPIQFPFPNELRCNNVQIKDNIRGFKSKP
GTAKPADLTPHLKPYTQQNNVELIYAFTTKEYKLFGYIVEMITPEQLLEK
VLQHPKIIKQATLLYLKKTLREDEEMGLTTTSTIMSLQDPISYTRMKYPS
KSINCKHLQCFDALWFLHSQLQIPTWQCPVCQIDIALENLAISEFVDDIL
QNCQKNVEQVELTSDGKWTAILDKLRPETHINLKVSDGSSEIFFKIKKTT
PLRRLMEAFAKRQGKEMDSLRFLYDGIRIQADQTPEDLDMEDNDIIEAHR
E
Ligand information
Ligand IDZN
InChIInChI=1S/Zn/q+2
InChIKeyPTFCDOFLOPIGGS-UHFFFAOYSA-N
SMILES
SoftwareSMILES
CACTVS 3.341[Zn++]
ACDLabs 10.04
OpenEye OEToolkits 1.5.0		[Zn+2]
FormulaZn
NameZINC ION
ChEMBLCHEMBL1236970
DrugBankDB14532
ZINC
PDB chain5jne Chain A Residue 601 [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
Receptor-Ligand Complex Structure
Global viewLocal viewStructure summary

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PDB5jne Capturing a substrate in an activated RING E3/E2-SUMO complex.
Resolution2.85 Å
Binding residue
(original residue number in PDB)		C377 H379 C400
Binding residue
(residue number reindexed from 1)		C205 H207 C228
Annotation score4
Enzymatic activity
Enzyme Commision number 2.3.2.-
6.3.2.-
Gene Ontology
Molecular Function
GO:0008270 zinc ion binding

View graph for
Molecular Function
External links
PDB RCSB:5jne, PDBe:5jne, PDBj:5jne
PDBsum5jne
PubMed27509863
UniProtQ04195|SIZ1_YEAST E3 SUMO-protein ligase SIZ1 (Gene Name=SIZ1);
Q12306|SMT3_YEAST Ubiquitin-like protein SMT3 (Gene Name=SMT3)

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