Structure of PDB 5jlx Chain A Binding Site BS01

Receptor Information

>5jlx Chain A (length=57) Species: 7227 (Drosophila melanogaster) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]

GRQTYTRYQTLELEKEFHFNRYLTRRRRIEIAHALSLTERQIKIWFQNRR
MKWKKEN

Ligand information

>5jlx Chain B (length=15) [Search DNA sequence] [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]

agaaagccattagag

Receptor-Ligand Complex Structure

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PDB	5jlx Stereospecific Effects of Oxygen-to-Sulfur Substitution in DNA Phosphate on Ion Pair Dynamics and Protein-DNA Affinity.
Resolution	2.748 Å
Binding residue (original residue number in PDB)	R5 T7 Y25 R31 K46 Q50 R53 M54 K57
Binding residue (residue number reindexed from 1)	R2 T4 Y22 R28 K43 Q47 R50 M51 K54
Binding affinity	PDBbind-CN: Kd=7.3nM

Enzymatic activity

Enzyme Commision number

Gene Ontology

	Molecular Function
GO:0000981	DNA-binding transcription factor activity, RNA polymerase II-specific
GO:0003677	DNA binding

	Biological Process
GO:0006355	regulation of DNA-templated transcription

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Molecular Function

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Biological Process

External links

PDB	RCSB:5jlx, PDBe:5jlx, PDBj:5jlx
PDBsum	5jlx
PubMed	27271797
UniProt	P02833\|ANTP_DROME Homeotic protein antennapedia (Gene Name=Antp)

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