Structure of PDB 5jls Chain A Binding Site BS01

Receptor Information
>5jls Chain A (length=134) Species: 301448 (Streptococcus pyogenes serotype M3) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
GTLEKKLDNLVNTILLKAENQKLTNTQEHILMLLSQQRLTNTDLAKALNI
SQAAVTKAIKSLVKQDMLAGTKDTVDARVTYFELTELAKPIASEHTHHHD
ETLNVYNRLLQKFSAKELEIVDKFVTVFAEELEG
Ligand information
Ligand IDZN
InChIInChI=1S/Zn/q+2
InChIKeyPTFCDOFLOPIGGS-UHFFFAOYSA-N
SMILES
SoftwareSMILES
CACTVS 3.341[Zn++]
ACDLabs 10.04
OpenEye OEToolkits 1.5.0		[Zn+2]
FormulaZn
NameZINC ION
ChEMBLCHEMBL1236970
DrugBankDB14532
ZINC
PDB chain5jls Chain A Residue 201 [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
Receptor-Ligand Complex Structure
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PDB5jls Crystal structure of Adhesin competence repressor (AdcR) from Streptococcus pyogenes
Resolution2.7 Å
Binding residue
(original residue number in PDB)		H42 H108 H112
Binding residue
(residue number reindexed from 1)		H29 H95 H99
Annotation score4
Enzymatic activity
Enzyme Commision number ?
Gene Ontology
Molecular Function
GO:0003677 DNA binding
GO:0003700 DNA-binding transcription factor activity
GO:0008270 zinc ion binding
GO:0046872 metal ion binding
Biological Process
GO:0006355 regulation of DNA-templated transcription

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Molecular Function
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Biological Process
External links
PDB RCSB:5jls, PDBe:5jls, PDBj:5jls
PDBsum5jls
PubMed
UniProtA0A0H2USX5

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