Structure of PDB 5jk4 Chain A Binding Site BS01

Receptor Information

>5jk4 Chain A (length=373) Species: 391008 (Stenotrophomonas maltophilia R551-3)

PTAVTGGGASLPADLYKGSADSILPANFSYAVTGSGTGKKAFLENNSALF
STTGTVHFAGSDSVLSSTELNTYNSTYNVSGDANRYGALVQIPSVATSVT
IPFNKAGSAVDLSVTQICGIFSGKINNWSQLAGLGRTGAIQVVYRGESSG
TSELLTRFLTSACQPADVSGTNLKLANGVPAFSVQSTFANLFTTVPSNFV
AAPATGGSALYNAVYAVDGRVGYVGPDVIPSLTDATKVAKVKSFSPDEVS
VQATLETAAPPTGAAAENPANWVPVFGNPSAGYPIAGYTNFVFGQCYKNA
TVGANVRGFLTRHYGSTVVNGVEQGPNDDAIRAHKFIPLTKAWRDAVRAR
FATATNAGAVNNPSTCSGIGRPL

Ligand information

• Ligand ID: PO4
• InChI: InChI=1S/H3O4P/c1-5(2,3)4/h(H3,1,2,3,4)/p-3
• InChIKey: NBIIXXVUZAFLBC-UHFFFAOYSA-K
• SMILES:
  CACTVS 3.341: [O-][P]([O-])([O-])=O
  ACDLabs 10.04: [O-]P([O-])([O-])=O
  OpenEye OEToolkits 1.5.0: [O-]P(=O)([O-])[O-]
• Formula: O4 P
• Name: PHOSPHATE ION
• DrugBank: DB14523
• PDB chain: 5jk4 Chain A Residue 501

Receptor-Ligand Complex Structure

Structure summary

• PDB: 5jk4 The 1.1 angstrom resolution structure of a periplasmic phosphate-binding protein from Stenotrophomonas maltophilia: a crystallization contaminant identified by molecular replacement using the entire Protein Data Bank.
• Resolution: 1.1 Å
• Binding residue (original residue number in PDB): A9 S10 L11 G34 S35 D62 R145 S149 G150 T151
• Binding residue (residue number reindexed from 1): A9 S10 L11 G34 S35 D62 R145 S149 G150 T151
• Annotation score: 1

Enzymatic activity

• Enzyme Commision number: 3.1.3.1: alkaline phosphatase.

Gene Ontology

Molecular Function

• GO:0004035 alkaline phosphatase activity
• GO:0016787 hydrolase activity

External links

• PDB: RCSB:5jk4, PDBe:5jk4, PDBj:5jk4
• PDBsum: 5jk4
• PubMed: 27487824
• UniProt: B4SL31