Structure of PDB 5jk0 Chain A Binding Site BS01
Receptor Information
>5jk0 Chain A (length=347) Species:
85962
(Helicobacter pylori 26695) [
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MKHPLEELKDPTENLLLWIGRFLRYKCTSLSNSQVKDQNKVFECLNELNQ
ACSSSQLEKVCKKARNAGLLGINTYALPLLKFHEYFSKARLIAFNSLKNI
DEVMLAEFLSVYTGGLSLATKKNYRIALLGLFSYIDKQNQDENEKSYIYN
ITLKKLPTHLNNEELEKFLESIDKIEMSAKVRARNRLLIKIIVFTGMRSN
EALQLKIKDFTLENGCYTILIKGKGDKYRAVMLKAFHIESLLKEWLIERE
LYPVKNDLLFCNQKGSALTQAYLYKQVERIINFAGLRREKNGAHMLRHSF
ATLLYQKRHDLILVQEALGHASLNTSRIYTHFDKQRLEEAASIWEEN
Ligand information
>5jk0 Chain E (length=30) [
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gagttatgaaaactgcacttttcaaacttt
Receptor-Ligand Complex Structure
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PDB
5jk0
Structural snapshots of Xer recombination reveal activation by synaptic complex remodeling and DNA bending.
Resolution
2.1 Å
Binding residue
(original residue number in PDB)
K62 R65 N66 L120 S121 A123 T124 N127 S193 R199 N277 Q278 T284 A286 Y287 K305 H309 A336
Binding residue
(residue number reindexed from 1)
K62 R65 N66 L116 S117 A119 T120 N123 S178 R184 N262 Q263 T269 A271 Y272 K290 H294 A321
Binding affinity
PDBbind-CN
: Kd=150nM
Enzymatic activity
Enzyme Commision number
?
Gene Ontology
Molecular Function
GO:0003677
DNA binding
GO:0009037
tyrosine-based site-specific recombinase activity
Biological Process
GO:0006310
DNA recombination
GO:0007059
chromosome segregation
GO:0015074
DNA integration
GO:0051301
cell division
Cellular Component
GO:0005737
cytoplasm
View graph for
Molecular Function
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Biological Process
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Cellular Component
External links
PDB
RCSB:5jk0
,
PDBe:5jk0
,
PDBj:5jk0
PDBsum
5jk0
PubMed
28009253
UniProt
O25386
|XERH_HELPY Tyrosine recombinase XerH (Gene Name=xerH)
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