Structure of PDB 5jju Chain A Binding Site BS01

Receptor Information
>5jju Chain A (length=325) Species: 419947 (Mycobacterium tuberculosis H37Ra) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
GARVDAVGAAALLSAAARVGVVCHVHPDADTIGAGLALALVLDGCGKRVE
VSFAAPATLPESLRSLPGCHLLVRPEVMRRDVDLVVTVDIPSVDRLGALG
DLTDSGRELLVIDHHASNDLFGTANFIDPSADSTTTMVAEILDAWGKPID
PRVAHCIYAGLATDTGSFRWASVRGYRLAARLVEIGVDNATVSRTLMDSH
PFTWLPLLSRVLGSAQLVSEAVGGRGLVYVVVDNREWVAARSEEVESIVD
IVRTTQQAEVAAVFKEVEPHRWSVSMRAKTVNLAAVASGFGGGGHRLAAG
YTTTGSIDDAVASLRAALGLTRAPP
Ligand information
Receptor-Ligand Complex Structure
Global viewLocal viewStructure summary

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PDB5jju Structural and biochemical insight into the mechanism of Rv2837c from Mycobacterium tuberculosis as a c-di-NMP phosphodiesterase
Resolution2.312 Å
Binding residue
(original residue number in PDB)
D45 R112 H132 D181 W187 S292 R294 G309 G310 G311 H312 A315 G317 Y318
Binding residue
(residue number reindexed from 1)
D28 R95 H115 D164 W170 S275 R277 G292 G293 G294 H295 A298 G300 Y301
Enzymatic activity
Enzyme Commision number ?
Gene Ontology
Molecular Function
GO:0000166 nucleotide binding
GO:0003676 nucleic acid binding
GO:0046872 metal ion binding

View graph for
Molecular Function
External links
PDB RCSB:5jju, PDBe:5jju, PDBj:5jju
PDBsum5jju
PubMed27371563
UniProtA5U6I9

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