Structure of PDB 5jji Chain A Binding Site BS01

Receptor Information

>5jji Chain A (length=405) Species: 83334 (Escherichia coli O157:H7)

MNLTELKNTPVSELITLGENMGRKQDIIFAILKQHAKSGEDIFGDGVLEI
LQDGFGFLRSADSSYLAGPDDIYVSPSQIRRFNLRTGDTISGKIRPPKEG
ERYFALLKVNEVNFDKPNKILFENLTPLHANSRLRMERGNGSTEDLTARV
LDLASPIGRGQRGLIVAPPKAGKTMLLQNIAQSIAYNHPDCVLMVLLIDE
RPEEVTEMQRLVKGEVVASTFDEPASRHVQVAEMVIEKAKRLVEHKKDVI
ILLDSITRLARAYNTVVPASGKVLTGGVDANALHRPKRFFGAARNVEEGG
SLTIIATALIDTGSKMDEVIYEEFKGTGNMELHLSRKIAEKRVFPAIDYN
RSGTRKEELLTTQEELQKMWILRKIIHPMGEIDAMEFLINKLAMTKTNDD
FFEMM

Ligand information

>5jji Chain G (length=7)

uuuuuuu

.......

Receptor-Ligand Complex Structure

Structure summary

• PDB: 5jji Molecular mechanisms of substrate-controlled ring dynamics and substepping in a nucleic acid-dependent hexameric motor.
• Resolution: 2.601 Å
• Binding residue (original residue number in PDB): V284 L285 G288
• Binding residue (residue number reindexed from 1): V273 L274 G277

Enzymatic activity

• Enzyme Commision number: 3.6.4.-

Gene Ontology

Molecular Function

• GO:0003676 nucleic acid binding
• GO:0003723 RNA binding
• GO:0004386 helicase activity
• GO:0005515 protein binding
• GO:0005524 ATP binding
• GO:0008186 ATP-dependent activity, acting on RNA
• GO:0016787 hydrolase activity
• GO:0016887 ATP hydrolysis activity
• GO:0042802 identical protein binding

Biological Process

• GO:0006353 DNA-templated transcription termination

Cellular Component

• GO:0005829 cytosol
• GO:0016020 membrane

External links

• PDB: RCSB:5jji, PDBe:5jji, PDBj:5jji
• PDBsum: 5jji
• PubMed: 27856760
• UniProt: P0AG30|RHO_ECOLI Transcription termination factor Rho (Gene Name=rho)