Structure of PDB 5jjg Chain A Binding Site BS01

Receptor Information
>5jjg Chain A (length=168) Species: 10090 (Mus musculus) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
DQSFLWNVFQRVDKDRSGVISDNELQQALSNGTWTPFNPVTVRSIISMFD
RENKAGVNFSEFTGVWKYITDWQNVFRTYDRDNSGMIDKNELKQALSGFG
YRLSDQFHDILIRKFDRQGRGQIAFDDFIQGCIVLQRLTDIFRRYDTDQD
GWIQVSYEQYLSMVFSIV
Ligand information
Ligand IDMG
InChIInChI=1S/Mg/q+2
InChIKeyJLVVSXFLKOJNIY-UHFFFAOYSA-N
SMILES
SoftwareSMILES
ACDLabs 10.04
OpenEye OEToolkits 1.5.0		[Mg+2]
CACTVS 3.341[Mg++]
FormulaMg
NameMAGNESIUM ION
ChEMBL
DrugBankDB01378
ZINC
PDB chain5jjg Chain A Residue 201 [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
Receptor-Ligand Complex Structure
Global viewLocal viewStructure summary

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PDB5jjg EF5 Is the High-Affinity Mg(2+) Site in ALG-2.
Resolution1.72 Å
Binding residue
(original residue number in PDB)		D36 D38 V42 E47
Binding residue
(residue number reindexed from 1)		D13 D15 V19 E24
Annotation score4
Enzymatic activity
Catalytic site (original residue number in PDB) F85 G108 I110
Catalytic site (residue number reindexed from 1) F62 G85 I87
Enzyme Commision number ?
Gene Ontology
Molecular Function
GO:0005509 calcium ion binding

View graph for
Molecular Function
External links
PDB RCSB:5jjg, PDBe:5jjg, PDBj:5jjg
PDBsum5jjg
PubMed27541325
UniProtP12815|PDCD6_MOUSE Programmed cell death protein 6 (Gene Name=Pdcd6)

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