Structure of PDB 5j9q Chain A Binding Site BS01

Receptor Information
>5j9q Chain A (length=292) Species: 559292 (Saccharomyces cerevisiae S288C) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
MTQNPHEVARVRNLNRIIMGKYEIEPWYFSPYPIELTDEDFIYIDDFTLQ
YFGSKKQYERYRKKCTLRHPPGNEIYRDDYVSFFEIDGRKQRTWCRNLCL
LSKLFLDHKTLYYDVDPFLFYCMTRRDELGHHLVGYFSKEKESADGYNVA
CILTLPQYQRMGYGKLLIEFSYELSKKENKVGSPQKPLSDLGLLSYRAYW
SDTLITLLVEHQKEITIDEISSMTSMTTTDILHTAKTLNILRYYKGQHII
FLNEDILDRYNRLKAKKRRTIDPNRLIWKPPVFTASQLRFAW
Ligand information
Receptor-Ligand Complex Structure
Global viewLocal viewStructure summary

[Spin on] [Spin off] [Reset]
[High quality] [Low quality]
[White background] [Black background]
[Spin on] [Spin off] [Reset]
[High quality] [Low quality]
[White background] [Black background]
PDB5j9q The NuA4 Core Complex Acetylates Nucleosomal Histone H4 through a Double Recognition Mechanism
Resolution3.25 Å
Binding residue
(original residue number in PDB)		H261 T263 F271 A303 Q338
Binding residue
(residue number reindexed from 1)		H108 T110 F118 A150 Q185
Enzymatic activity
Catalytic site (original residue number in PDB) C304 Q338
Catalytic site (residue number reindexed from 1) C151 Q185
Enzyme Commision number 2.3.1.-
2.3.1.48: histone acetyltransferase.
Gene Ontology
Molecular Function
GO:0004402 histone acetyltransferase activity
Biological Process
GO:0006355 regulation of DNA-templated transcription

View graph for
Molecular Function
View graph for
Biological Process
External links
PDB RCSB:5j9q, PDBe:5j9q, PDBj:5j9q
PDBsum5j9q
PubMed27594449
UniProtQ08649|ESA1_YEAST Histone acetyltransferase ESA1 (Gene Name=ESA1)

[Back to BioLiP]