Structure of PDB 5j53 Chain A Binding Site BS01

Receptor Information
>5j53 Chain A (length=479) Species: 279238 (Novosphingobium aromaticivorans DSM 12444) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
AQFPNTPSFTGFNTPSRIEADIADLAHEGTIPQGLNGAFYRVQPDPQFPP
RLDDDIAFNGDGMITRFHIHDGQVDFRQRWAKTDKWKLENAAGKALFGAY
RNPLTDDEAVKGEIRSTANTNAFVFGGKLWAMKEDSPALVMDPATMETFG
FEKFGGKMTGQTFTAHPKVDPKTGNMVAIGYAASGLCTDDVTYMEVSPEG
ELVREVWFKVPYYCMMHDFGITEDYLVLHIVPSIGSWERLEQGKPHFGFD
TTMPVHLGIIPRRDGVRQEDIRWFTRDNCFASHVLNAWQEGTKIHFVTCE
AKNNMFPFFPDVHGAPFNGMEAMSHPTDWVVDMASNGEDFAGIVKLSDTA
AEFPRIDDRFTGQKTRHGWFLEMDMKRPVELLMNCLFHKDFETGREQHWW
CGPVSSLQEPCFVPRAKDAPEGDGWIVQVCNRLEEQRSDLLIFDALDIEK
GPVATVNIPIRLRFGLHGNWANADEIGLA
Ligand information
Ligand IDFE
InChIInChI=1S/Fe/q+3
InChIKeyVTLYFUHAOXGGBS-UHFFFAOYSA-N
SMILES
SoftwareSMILES
ACDLabs 10.04
CACTVS 3.341
OpenEye OEToolkits 1.5.0		[Fe+3]
FormulaFe
NameFE (III) ION
ChEMBL
DrugBankDB13949
ZINC
PDB chain5j53 Chain A Residue 501 [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
Receptor-Ligand Complex Structure
Global viewLocal viewStructure summary

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PDB5j53 Structure and mechanism of NOV1, a resveratrol-cleaving dioxygenase.
Resolution1.61 Å
Binding residue
(original residue number in PDB)		H167 H218 H284 H476
Binding residue
(residue number reindexed from 1)		H166 H217 H283 H467
Annotation score4
Enzymatic activity
Enzyme Commision number 1.13.11.-
Gene Ontology
Molecular Function
GO:0010436 carotenoid dioxygenase activity
GO:0016702 oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of two atoms of oxygen
GO:0046872 metal ion binding
GO:0051213 dioxygenase activity
Biological Process
GO:0016121 carotene catabolic process

View graph for
Molecular Function
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Biological Process
External links
PDB RCSB:5j53, PDBe:5j53, PDBj:5j53
PDBsum5j53
PubMed27911781
UniProtQ2GA76

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