Structure of PDB 5j4h Chain A Binding Site BS01

Receptor Information
>5j4h Chain A (length=225) Species: 186497 (Pyrococcus furiosus DSM 3638) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
ATIGRISTGSKSLDKLLGGGIETQAITEVFGEFGSGKTQLAHTLAVMVQL
PPEEGGLNGSAMYIDTENTFRPERLREIAQNRGLDPDEVLDNVAYARAFN
SNHQMLLVQQAEDMIKELLNTDRPVKLLIVDSLTSHFRSEYIGRGALAER
QQKLAKHLADLHRLANLYDIAVFVTNQVHILAHSATLRVYLRKGKGGKRI
ARLIDAPHLPEGEAVFSITEKGIED
Ligand information
Ligand ID1F1
InChIInChI=1S/C9H7NO2/c11-9(12)7-2-1-6-3-4-10-8(6)5-7/h1-5,10H,(H,11,12)
InChIKeyGHTDODSYDCPOCW-UHFFFAOYSA-N
SMILES
SoftwareSMILES
CACTVS 3.352OC(=O)c1ccc2cc[nH]c2c1
ACDLabs 11.02O=C(O)c1ccc2c(c1)ncc2
OpenEye OEToolkits 1.7.0c1cc(cc2c1cc[nH]2)C(=O)O
FormulaC9 H7 N O2
Name1H-indole-6-carboxylic acid
ChEMBLCHEMBL1229732
DrugBank
ZINCZINC000000058267
PDB chain5j4h Chain A Residue 401 [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
Receptor-Ligand Complex Structure
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PDB5j4h Engineering Archeal Surrogate Systems for the Development of Protein-Protein Interaction Inhibitors against Human RAD51.
Resolution1.374 Å
Binding residue
(original residue number in PDB)		I171 A201 A203 Q217
Binding residue
(residue number reindexed from 1)		I64 A94 A96 Q110
Annotation score1
Enzymatic activity
Enzyme Commision number ?
Gene Ontology
Molecular Function
GO:0003677 DNA binding
GO:0003684 damaged DNA binding
GO:0005524 ATP binding
GO:0008094 ATP-dependent activity, acting on DNA
GO:0016887 ATP hydrolysis activity
GO:0140664 ATP-dependent DNA damage sensor activity
Biological Process
GO:0006259 DNA metabolic process
GO:0006281 DNA repair
GO:0006310 DNA recombination

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Molecular Function
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Biological Process
External links
PDB RCSB:5j4h, PDBe:5j4h, PDBj:5j4h
PDBsum5j4h
PubMed27725183
UniProtO74036|RADA_PYRFU DNA repair and recombination protein RadA (Gene Name=radA)

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