Structure of PDB 5j19 Chain A Binding Site BS01
Receptor Information
>5j19 Chain A (length=221) Species:
9606
(Homo sapiens) [
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DCHLSDMLQQLHSVNASKPSERVRQEEAEDPACIPIFWVSKWVDYSDKYG
LGYQLCDNSVGVLFNDSTRLILYNDGDSLQYIERDGTESYLTVSSHPNSL
MKKITLLKYFRNYMSEHLLKAGANITPREGDELARLPYLRTWFRTRSAII
LHLSNGSVQINFFQDHTKLILCPLMAAVTYIDEKRDFRTYRLSLLEEYGC
CKELASRLRYARTMVDKLLSS
Ligand information
>5j19 Chain D (length=8) Species:
7227
(Drosophila melanogaster) [
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AAFSSTPK
Receptor-Ligand Complex Structure
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PDB
5j19
Phospho-Pon Binding-Mediated Fine-Tuning of Plk1 Activity
Resolution
2.0 Å
Binding residue
(original residue number in PDB)
W414 V415 D416 Y417 E488 H489 L490 L491 R516 H538 K540
Binding residue
(residue number reindexed from 1)
W42 V43 D44 Y45 E116 H117 L118 L119 R144 H166 K168
Enzymatic activity
Enzyme Commision number
2.7.11.21
: polo kinase.
External links
PDB
RCSB:5j19
,
PDBe:5j19
,
PDBj:5j19
PDBsum
5j19
PubMed
27238966
UniProt
P53350
|PLK1_HUMAN Serine/threonine-protein kinase PLK1 (Gene Name=PLK1)
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