Structure of PDB 5izu Chain A Binding Site BS01
Receptor Information
>5izu Chain A (length=124) Species:
10090
(Mus musculus) [
Search protein sequence
] [
Download receptor structure
] [
Download structure with residue number starting from 1
] [
View receptor structure
]
RTKRLFRHYTVGSYDSLTSHSDYVIDDKVAILQKRDHEGFGFVLRGAKAE
TPIEEFTPTPAFPALQYLESVDVEGVAWRAGLRTGDFLIEVNGVNVVKVG
HKQVVGLIRQGGNRLVMKVVSVTR
Ligand information
>5izu Chain B (length=15) Species:
10090
(Mus musculus) [
Search peptide sequence
] [
Download ligand structure
] [
Download structure with residue number starting from 1
] [
View ligand structure
]
ADSIEIYIPEAQTRL
Receptor-Ligand Complex Structure
Global view
Local view
Structure summary
[
Spin on
] [
Spin off
] [
Reset
]
[
High quality
] [
Low quality
]
[
White background
] [
Black background
]
[
Spin on
] [
Spin off
] [
Reset
]
[
High quality
] [
Low quality
]
[
White background
] [
Black background
]
PDB
5izu
A binding site outside the canonical PDZ domain determines the specific interaction between Shank and SAPAP and their function
Resolution
2.494 Å
Binding residue
(original residue number in PDB)
G580 F581 F583 V584 L585 R586 G587 A588 K589 Y608 E610 H642
Binding residue
(residue number reindexed from 1)
G39 F40 F42 V43 L44 R45 G46 A47 K48 Y67 E69 H101
Enzymatic activity
Enzyme Commision number
?
External links
PDB
RCSB:5izu
,
PDBe:5izu
,
PDBj:5izu
PDBsum
5izu
PubMed
27185935
UniProt
Q4ACU6
|SHAN3_MOUSE SH3 and multiple ankyrin repeat domains protein 3 (Gene Name=Shank3)
[
Back to BioLiP
]
