Structure of PDB 5izo Chain A Binding Site BS01

Receptor Information
>5izo Chain A (length=292) Species: 224308 (Bacillus subtilis subsp. subtilis str. 168) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
FQSMASMKTELIRTISLYDTIILHRHVRPDPDAYGSQCGLTEILRETYPE
KNIFAVGTPEPSLSFLYSLDEVDNETYEGALVIVCDTANQERIDDQRYPS
GAKLMKIDAHPNEDPYGDLLWVDTSASSVSEMIYELYLEGKEHGWKLNTK
AAELIYAGIVGDTGRFLFPNTTEKTLKYAGELIQYPFSSSELFNQLYETK
LNVVKLNGFIFQNVSLSENGAASVFIKKDTLEKFGTTASEASQLVGTLGN
ISGIRWVFFVEERVRFRSKGPVINGLKYNHPDRILDLELCKE
Ligand information
Ligand IDMN
InChIInChI=1S/Mn/q+2
InChIKeyWAEMQWOKJMHJLA-UHFFFAOYSA-N
SMILES
SoftwareSMILES
ACDLabs 10.04
OpenEye OEToolkits 1.5.0		[Mn+2]
CACTVS 3.341[Mn++]
FormulaMn
NameMANGANESE (II) ION
ChEMBL
DrugBankDB06757
ZINC
PDB chain5izo Chain A Residue 401 [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
Receptor-Ligand Complex Structure
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PDB5izo Structural Basis for the Bidirectional Activity of Bacillus nanoRNase NrnA.
Resolution1.95 Å
Binding residue
(original residue number in PDB)		H20 D24 D80
Binding residue
(residue number reindexed from 1)		H26 D30 D86
Annotation score1
Enzymatic activity
Enzyme Commision number 3.1.-.-
3.1.3.7: 3'(2'),5'-bisphosphate nucleotidase.
Gene Ontology
Molecular Function
GO:0003676 nucleic acid binding
GO:0004527 exonuclease activity
GO:0008441 3'(2'),5'-bisphosphate nucleotidase activity

View graph for
Molecular Function
External links
PDB RCSB:5izo, PDBe:5izo, PDBj:5izo
PDBsum5izo
PubMed28894100
UniProtO34600|NRNA_BACSU Bifunctional oligoribonuclease and PAP phosphatase NrnA (Gene Name=nrnA)

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