Structure of PDB 5iyx Chain A Binding Site BS01

Receptor Information

>5iyx Chain A (length=596) Species: 3702 (Arabidopsis thaliana) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]

LNQDATILRQAKLGLSDPAQSLSSWSDNNDVTPCKWLGVSCDATSNVVSV
DLSSFMLVGPFPSILCHLPSLHSLSLYNNSINGSLSADDFDTCHNLISLD
LSENLLVGSIPKSLPFNLPNLKFLEISGNNLSDTIPSSFGEFRKLESLNL
AGNFLSGTIPASLGNVTTLKELKLAYNLFSPSQIPSQLGNLTELQVLWLA
GCNLVGPIPPSLSRLTSLVNLDLTFNQLTGSIPSWITQLKTVEQIELFNN
SFSGELPESMGNMTTLKRFDASMNKLTGKIPDNLNLLNLESLNLFENMLE
GPLPESITRSKTLSELKLFNNRLTGVLPSQLGANSPLQYVDLSYNRFSGE
IPANVCGEGKLEYLILIDNSFSGEISNNLGKCKSLTRVRLSNNKLSGQIP
HGFWGLPRLSLLELSDNSFTGSIPKTIIGAKNLSNLRISKNRFSGSIPNE
IGSLNGIIEISGAENDFSGEIPESLVKLKQLSRLDLSKNQLSGEIPRELR
GWKNLNELNLANNHLSGEIPKEVGILPVLNYLDLSSNQFSGEIPLELQNL
KLNVLNLSYNHLSGKIPPLYANKIYAHDFIGNPGLCVDLDGLCRKI

Ligand information

>5iyx Chain B (length=14) Species: 3702 (Arabidopsis thaliana) [Search peptide sequence] [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]

YVPIPPSAPSKRHN

Receptor-Ligand Complex Structure

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Structure summary

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PDB	5iyx Mechanistic insight into a peptide hormone signaling complex mediating floral organ abscission.
Resolution	2.43 Å
Binding residue (original residue number in PDB)	E123 Y196 W218 N240 D242 Q264 E266 F268 D290 N313 F315 E316 K337 F339 D361 Y383 R407 R409
Binding residue (residue number reindexed from 1)	E103 Y176 W198 N220 D222 Q244 E246 F248 D270 N293 F295 E296 K317 F319 D341 Y363 R387 R389

Enzymatic activity

Enzyme Commision number

2.7.10.1: receptor protein-tyrosine kinase.
2.7.11.1: non-specific serine/threonine protein kinase.

External links

PDB	RCSB:5iyx, PDBe:5iyx, PDBj:5iyx
PDBsum	5iyx
PubMed	27058169
UniProt	P47735\|RLK5_ARATH Receptor-like protein kinase 5 (Gene Name=RLK5)

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