Structure of PDB 5ixt Chain A Binding Site BS01

Receptor Information

>5ixt Chain A (length=595) Species: 3702 (Arabidopsis thaliana) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]

MGSLNQDATILRQAKLGLSDPAQSLSSWSDVTPCKWLGVSCDATSNVVSV
DLSSFMLVGPFPSILCHLPSLHSLSLYNNSINGSLSADDFDTCHNLISLD
LSENLLVGSIPKSLPFNLPNLKFLEISGNNLSDTIPSSFGEFRKLESLNL
AGNFLSGTIPASLGNVTTLKELKLAYNLFSPSQIPSQLGNLTELQVLWLA
GCNLVGPIPPSLSRLTSLVNLDLTFNQLTGSIPSWITQLKTVEQIELFNN
SFSGELPESMGNMTTLKRFDASMNKLTGKIPDNLNLLNLESLNLFENMLE
GPLPESITRSKTLSELKLFNNRLTGVLPSQLGANSPLQYVDLSYNRFSGE
IPANVCGEGKLEYLILIDNSFSGEISNNLGKCKSLTRVRLSNNKLSGQIP
HGFWGLPRLSLLELSDNSFTGSIPKTIIGAKNLSNLRISKNRFSGSIPNE
IGSLNGIIEISGAENDFSGEIPESLVKLKQLSRLDLSKNQLSGEIPRELR
GWKNLNELNLANNHLSGEIPKEVGILPVLNYLDLSSNQFSGEIPLELQNL
KLNVLNLSYNHLSGKIPPLYANKIYAHDFIGNPGLCVDLDGLCRK

Ligand information

>5ixt Chain B (length=12) Species: 3702 (Arabidopsis thaliana) [Search peptide sequence] [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]

PIPPSAPSKRHN

Receptor-Ligand Complex Structure

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Structure summary

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PDB	5ixt Mechanistic insight into a peptide hormone signaling complex mediating floral organ abscission.
Resolution	1.94 Å
Binding residue (original residue number in PDB)	Y196 W218 D242 Q264 E266 F268 R288 D290 N313 F315 K337 F339 D361 Y364 Y383 I385 R407 R409
Binding residue (residue number reindexed from 1)	Y176 W198 D222 Q244 E246 F248 R268 D270 N293 F295 K317 F319 D341 Y344 Y363 I365 R387 R389

Enzymatic activity

Enzyme Commision number

2.7.10.1: receptor protein-tyrosine kinase.
2.7.11.1: non-specific serine/threonine protein kinase.

External links

PDB	RCSB:5ixt, PDBe:5ixt, PDBj:5ixt
PDBsum	5ixt
PubMed	27058169
UniProt	P47735\|RLK5_ARATH Receptor-like protein kinase 5 (Gene Name=RLK5)

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