Structure of PDB 5ivx Chain A Binding Site BS01
Receptor Information
>5ivx Chain A (length=274) Species:
10090
(Mus musculus) [
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MSHSLRYFVTAVSRPGFGEPRYMEVGYVDNTEFVRFDSDAENPRYEPRAR
WIEQEGPEYWERETRRAKGNEQSFRVDLRTALRYYNQSAGGSHTLQWMAG
CDVESDGRLLRGYWQFAYDGCDYIALNEDLKTWTAADMAAQITRRKWEQA
GAAERDRAYLEGECVEWLRRYLKNGNATLLRTDPPKAHVTHHRRPEGDVT
LRCWALGFYPADITLTWQLNGEELTQEMELVETRPAGDGTFQKWASVVVP
LGKEQKYTCHVEHEGLPEPLTLRW
Ligand information
>5ivx Chain P (length=10) Species:
9606
(Homo sapiens) [
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RGPGRAFVTI
Receptor-Ligand Complex Structure
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PDB
5ivx
An allosteric site in the T-cell receptor C beta domain plays a critical signalling role.
Resolution
2.1 Å
Binding residue
(original residue number in PDB)
Y7 R62 E63 R66 N70 S73 F74 D77 Y84 W97 W114 F116 T143 K146 W147 Y159 E163 W167 Y171
Binding residue
(residue number reindexed from 1)
Y7 R62 E63 R66 N70 S73 F74 D77 Y84 W97 W114 F116 T143 K146 W147 Y159 E163 W167 Y171
Enzymatic activity
Enzyme Commision number
?
External links
PDB
RCSB:5ivx
,
PDBe:5ivx
,
PDBj:5ivx
PDBsum
5ivx
PubMed
28508865
UniProt
P01900
|HA12_MOUSE H-2 class I histocompatibility antigen, D-D alpha chain (Gene Name=H2-D1)
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