Structure of PDB 5ik8 Chain A Binding Site BS01

Receptor Information
>5ik8 Chain A (length=381) Species: 10090 (Mus musculus) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
APLAMVHGPCVAESEPALLTGSKQFGLSRNSHIAIAFDDTKVKNRLTIEL
EVRTEAESGLLFYMARINHADFATVQLRNGFPYFSYDLGSGDTSTMIPTK
INDGQWHKIKIVRVKQEGILYVDDASSQTISPKKADILDVVGILYVGGLP
INYTTRRIGPVTYSLDGCVRNLHMEQAPVDLDQPTSSFHVGTCFANAESG
TYFDGTGFAKAVGGFKVGLDLLVEFEFRTTRPTGVLLGVSSQKMDGMGIE
MIDEKLMFHVDNGAGRFTAIYDAEIPGHMCNGQWHKVTAKKIKNRLELVV
DGNQVDAQSPNSASTSADTNDPVFVGGFPGGLNQFGLTTNIRFRGCIRSL
KLTKGTGKPLEVNFAKALELRGVQPVSCPTT
Ligand information
Ligand IDCA
InChIInChI=1S/Ca/q+2
InChIKeyBHPQYMZQTOCNFJ-UHFFFAOYSA-N
SMILES
SoftwareSMILES
CACTVS 3.341[Ca++]
ACDLabs 10.04
OpenEye OEToolkits 1.5.0		[Ca+2]
FormulaCa
NameCALCIUM ION
ChEMBL
DrugBankDB14577
ZINC
PDB chain5ik8 Chain A Residue 4001 [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
Receptor-Ligand Complex Structure
Global viewLocal viewStructure summary

[Spin on] [Spin off] [Reset]
[High quality] [Low quality]
[White background] [Black background]
[Spin on] [Spin off] [Reset]
[High quality] [Low quality]
[White background] [Black background]
PDB5ik8 Structural basis of laminin binding to the LARGE glycans on dystroglycan.
Resolution2.0 Å
Binding residue
(original residue number in PDB)		D2808 L2825 I2874 D2876
Binding residue
(residue number reindexed from 1)		D71 L88 I137 D139
Annotation score4
Enzymatic activity
Enzyme Commision number ?
External links
PDB RCSB:5ik8, PDBe:5ik8, PDBj:5ik8
PDBsum5ik8
PubMed27526028
UniProtQ60675|LAMA2_MOUSE Laminin subunit alpha-2 (Gene Name=Lama2)

[Back to BioLiP]