Structure of PDB 5id6 Chain A Binding Site BS01

Receptor Information
>5id6 Chain A (length=1209) Species: 1410628 (Lachnospiraceae bacterium ND2006) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
AASKLEKFTNCYSLSKTLRFKAIPVGKTQENIDNKRLLVEDEKRAEDYKG
VKKLLDRYYLSFINDVLHSIKLKNLNNYISLFRKKTRTEKENKELENLEI
NLRKEIAKAFKGAAGYKSLFKKDIIETILPEAAKDEIALVNSFNGFTTAF
TGFFDNRENMFSEEAKSTSIAFRCINENLTRYISNMDIFEKVDAIFDKHE
VQEIKEKILNSDYDVEDFFEGEFFNFVLTQEGIDVYNAIIGGFVTESGEK
IKGLNEYINLYNAKTKQALPKFKPLYKQVEGYTSDEEVLEVFRNTLNKNS
EIFSSIKKLEKLFKNFDEYSSAGIFVKNGPAISTISKDIFGEWNLIRDKW
NAEYDDIHLKKKAVVTEKYEDDRRKSFKKIGSFSLEQLQEYADADLSVVE
KLKEIIIQKVDEIYKVYGSSEKLFDADFVLEKSLKKNDAVVAIMKDLLDS
VKSFENYIKAFFGEGKETNRDESFYGDFVLAYDILLKVDHIYDAIRNYVT
QKPYSKDKFKLYFQNPQFMGGWDKDKETDYRATILRYGSKYYLAIMDKKY
AKCLQKIDKDDVNGNYEKINYKLLPGPNKMLPKVFFSKKWMAYYNPSEDI
QKIYKNGTFKKGDMFNLNDCHKLIDFFKDSISRYPKWSNAYDFNFSETEK
YKDIAGFYREVEEQGYKVSFESASKKEVDKLVEEGKLYMFQIYNKDFSDK
SHGTPNLHTMYFKLLFDENNHGQIRLSGGAELFMRRASLKKEELVVHPAN
SPIANKNPDNPKKTTTLSYDVYKDKRFSEDQYELHIPIAINKCPKNIFKI
NTEVRVLLKHDDNPYVIGIDRGERNLLYIVVVDGKGNIVEQYSLNEIINN
FNGIRIKTDYHSLLDKKEKERFEARQNWTSIENIKELKAGYISQVVHKIC
ELVEKYDAVIALEDLNSGFKNSRVKVEKQVYQKFEKMLIDKLNYMVDKKS
NPCATGGALKGYQITNKFESFKSMSTQNGFIFYIPAWLTSKIDPSTGFVN
LLKTKYTSIADSKKFISSFDRIMYVPEEDLFEFALDYKNFSRTDADYIKK
WKLYSYGNRIRIFAAAAWEEVCLTSAYKELFNKYGINYQQGDIRALLCEQ
SDKAFYSSFMALMSLMLQMRNSITGRTDVDFLISPVKNSDGIFYDSRNYE
AQENAILPKNADANGAYNIARKVLWAIGQFKKAEDEKLDKVKIAISNKEW
LEYAQTSVK
Ligand information
>5id6 Chain G (length=21) [Search RNA sequence] [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
aauuucuacuaaguguagauc
....<<<<<.....>>>>>..
Receptor-Ligand Complex Structure
Global viewLocal viewStructure summary

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PDB5id6 The crystal structure of Cpf1 in complex with CRISPR RNA
Resolution2.382 Å
Binding residue
(original residue number in PDB)
K15 T16 R18 F19 K20 K514 Y516 K518 N706 K707 S710 K712 H714 G715 T716 N718 L719 H720 R747 H759 I765 A766 N767 K768 N769 N772 K774 T777 L779 Y781 V783 Y784 K785 D786 R788 N861 N862 F863 Y872 L875 S905 Q906 H909 K953 K960
Binding residue
(residue number reindexed from 1)
K16 T17 R19 F20 K21 K502 Y504 K506 N694 K695 S698 K700 H702 G703 T704 N706 L707 H708 R735 H747 I753 A754 N755 K756 N757 N760 K762 T765 L767 Y769 V771 Y772 K773 D774 R776 N849 N850 F851 Y860 L863 S893 Q894 H897 K941 K948
Binding affinityPDBbind-CN: Kd=2.86nM
Enzymatic activity
Enzyme Commision number ?
Gene Ontology
Molecular Function
GO:0046872 metal ion binding

View graph for
Molecular Function
External links
PDB RCSB:5id6, PDBe:5id6, PDBj:5id6
PDBsum5id6
PubMed27096363
UniProtA0A182DWE3

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