Structure of PDB 5ict Chain A Binding Site BS01

Receptor Information
>5ict Chain A (length=266) Species: 7227 (Drosophila melanogaster) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
GSYDRNHTYIVSSLLEEPYLSLKQYTYGESLVGNDRFEGYCKDLADMLAA
QLGIKYEIRLVQDGNYGAENQYAPGGWDGMVGELIRKEADIAISAMTITA
ERERVIDFSKPFMTLGISIMIKKGTPIKTPEDLTMQTDVNYGTLLYGSTW
EFFRRSQIGLHNKMWEYMNANQHHSVHTTDEGIRRVRQSKGKYALLVESP
KNEYVNARPPCDTMKVGRNIDTKGFGVATPIGSPLRKRLNEAVLTLKENG
ELLRIRNKWWFDKTEC
Ligand information
Ligand IDGLU
InChIInChI=1S/C5H9NO4/c6-3(5(9)10)1-2-4(7)8/h3H,1-2,6H2,(H,7,8)(H,9,10)/t3-/m0/s1
InChIKeyWHUUTDBJXJRKMK-VKHMYHEASA-N
SMILES
SoftwareSMILES
ACDLabs 12.01O=C(O)C(N)CCC(=O)O
OpenEye OEToolkits 1.7.0C(CC(=O)O)C(C(=O)O)N
OpenEye OEToolkits 1.7.0C(CC(=O)O)[C@@H](C(=O)O)N
CACTVS 3.370N[C@@H](CCC(O)=O)C(O)=O
CACTVS 3.370N[CH](CCC(O)=O)C(O)=O
FormulaC5 H9 N O4
NameGLUTAMIC ACID
ChEMBLCHEMBL575060
DrugBankDB00142
ZINCZINC000001482113
PDB chain5ict Chain A Residue 301 [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
Receptor-Ligand Complex Structure
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PDB5ict Novel Functional Properties of Drosophila CNS Glutamate Receptors.
Resolution1.68 Å
Binding residue
(original residue number in PDB)		Y66 T97 R102 L144 S148 T149 E198
Binding residue
(residue number reindexed from 1)		Y66 T97 R102 L144 S148 T149 E198
Annotation score4
Enzymatic activity
Enzyme Commision number ?
Gene Ontology
Molecular Function
GO:0015276 ligand-gated monoatomic ion channel activity
Cellular Component
GO:0016020 membrane

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Molecular Function
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Cellular Component
External links
PDB RCSB:5ict, PDBe:5ict, PDBj:5ict
PDBsum5ict
PubMed27889096
UniProtQ03445|GLR1_DROME Glutamate receptor 1 (Gene Name=GluRIA)

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