Structure of PDB 5i70 Chain A Binding Site BS01

Receptor Information
>5i70 Chain A (length=315) Species: 57266 (Plasmodium falciparum 7G8) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
SIELDDVANLMFYGEGQIGTNKQPFMFIFDTGSANLWVPSVNCDSIGCST
KHLYDASASKSYEKDGTKVEISYGSGTVRGYFSKDVISLGDLSLPYKFIE
VTDADDLEPIYSGSEFDGILGLGWKDLSIGSIDPVVVELKKQNKIDNALF
TFYLPVHDHVGYLTIGGIESDFYEGPLTYEKLNHDLYWQIDLDIHFGKYV
MQKANAVVDSGTSTITAPTSFLNKFFVIKVPFYVTTCDNDDLPTLEFHSR
NNKYTLEPEFYMDPLSDIDPALCMLYILPVDIDDNTFILGDPFMRKYFTV
FDYEKESVGFAVAKN
Ligand information
Receptor-Ligand Complex Structure
Global viewLocal viewStructure summary

[Spin on] [Spin off] [Reset]
[High quality] [Low quality]
[White background] [Black background]
[Spin on] [Spin off] [Reset]
[High quality] [Low quality]
[White background] [Black background]
PDB5i70 Crystal Structure of plasmepsin IV
Resolution3.0 Å
Binding residue
(original residue number in PDB)		D34 G36 S76 Y77 G78 S79 I123 Y192 D214 G216 T217 S218 I294
Binding residue
(residue number reindexed from 1)		D30 G32 S72 Y73 G74 S75 I119 Y187 D209 G211 T212 S213 I282
Enzymatic activity
Catalytic site (original residue number in PDB) D34 S37 N39 W41 Y77 D214 T217
Catalytic site (residue number reindexed from 1) D30 S33 N35 W37 Y73 D209 T212
Enzyme Commision number ?
Gene Ontology
Molecular Function
GO:0004190 aspartic-type endopeptidase activity
Biological Process
GO:0006508 proteolysis

View graph for
Molecular Function
View graph for
Biological Process
External links
PDB RCSB:5i70, PDBe:5i70, PDBj:5i70
PDBsum5i70
PubMed
UniProtW7FF86

[Back to BioLiP]