Structure of PDB 5i3u Chain A Binding Site BS01 |
| >5i3u Chain A (length=550) Species: 11678 (Human immunodeficiency virus type 1 BH10)
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PIETVPVKLKPGMDGPKVKQWPLTEEKIKALVEICTEMEKEGKISKIGPE
NPYNTPVFAIKKKDSTKWRKLVDFRELNKRTQDFWEVQLGIPHPAGLKKK
KSVTVLDVGDAYFSVPLDEDFRKYTAFTIPSINNETPGIRYQYNVLPQGW
KGSPAIFQSSMTKILEPFKKQNPDIVIYQYMDDLYVGSDLEIGQHRTKIE
ELRQHLLRWGLTTPDKKHQKEPPFLWMGYELHPDKWTVQPIVLPEKDSWT
VNDIQKLVGKLNWASQIYPGIKVRQLSKLLRGTKALTEVIPLTEEAELEL
AENREILKEPVHGVYYDPSKDLIAEIQKQGQGQWTYQIYQEPFKNLKTGK
YARMRGAHTNDVKQLTEAVQKITTESIVIWGKTPKFKLPIQKETWETWWT
EYWQATWIPEWEFVNTPPLVKLWYQLEKEPIVGAETFYVDGAANRETKLG
KAGYVTNKGRQKVVPLTNTTNQKTELQAIYLALQDSGLEVNIVTDSQYAL
GIIQAQPDKSESELVNQIIEQLIKKEKVYLAWVPAHKGIGGNEQVDKLVS |
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| PDB | 5i3u Conformational States of HIV-1 Reverse Transcriptase for Nucleotide Incorporation vs Pyrophosphorolysis-Binding of Foscarnet. |
| Resolution | 3.0 Å |
Binding residue
(original residue number in PDB) | W24 F61 L74 D76 R78 E89 I94 Y115 Q151 G152 K154 P157 Y183 M184 D185 D186 M230 G231 N255 Q258 K259 G262 K263 W266 S280 R284 G285 K353 G359 H361 R448 T473 Q475 K476 Q500 Y501 |
Binding residue
(residue number reindexed from 1) | W21 F58 L71 D73 R75 E86 I91 Y112 Q148 G149 K151 P154 Y180 M181 D182 D183 M227 G228 N252 Q255 K256 G259 K260 W263 S277 R281 G282 K350 G356 H358 R445 T470 Q472 K473 Q497 Y498 |
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