Structure of PDB 5i2b Chain A Binding Site BS01

Receptor Information
>5i2b Chain A (length=167) Species: 396596 (Burkholderia ambifaria IOP40-10) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
HMIREILKMGDPRLLEVAKPVAQFDTPELHEIVADMFETMHHANGAGLAA
PQIGIGLQIIIFGFNRYPDAPPVPETVLINPKLEYMPPDMEEGWEGCLSV
PGMRGVVSRYAKVRYSGYDQFGAKIDRVAEGFHARVVQHEYDHLIGKLYP
MRITDFTRFGFTEVLFP
Ligand information
Ligand IDZN
InChIInChI=1S/Zn/q+2
InChIKeyPTFCDOFLOPIGGS-UHFFFAOYSA-N
SMILES
SoftwareSMILES
CACTVS 3.341[Zn++]
ACDLabs 10.04
OpenEye OEToolkits 1.5.0		[Zn+2]
FormulaZn
NameZINC ION
ChEMBLCHEMBL1236970
DrugBankDB14532
ZINC
PDB chain5i2b Chain A Residue 201 [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
Receptor-Ligand Complex Structure
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PDB5i2b Crystal structure of a peptide deformylase from Burkholderia ambifaria with actinonin
Resolution1.7 Å
Binding residue
(original residue number in PDB)		C99 H141 H145
Binding residue
(residue number reindexed from 1)		C97 H139 H143
Annotation score1
Enzymatic activity
Catalytic site (original residue number in PDB) G46 Q51 C99 L100 H141 E142 H145
Catalytic site (residue number reindexed from 1) G47 Q52 C97 L98 H139 E140 H143
Enzyme Commision number 3.5.1.88: peptide deformylase.
Gene Ontology
Molecular Function
GO:0016787 hydrolase activity
GO:0042586 peptide deformylase activity
GO:0046872 metal ion binding
Biological Process
GO:0006412 translation
GO:0018206 peptidyl-methionine modification

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Molecular Function
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Biological Process
External links
PDB RCSB:5i2b, PDBe:5i2b, PDBj:5i2b
PDBsum5i2b
PubMed
UniProtB1FPK4

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