Structure of PDB 5hyr Chain A Binding Site BS01
Receptor Information
>5hyr Chain A (length=231) Species:
9606
(Homo sapiens) [
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ALSLTADQMVSALLDAEPPILYSEYDPTRPFSEASMMGLLTNLADRELVH
MINWAKRVPGFVDLTLHDQVHLLECAWLEILMIGLVWRSMEHPGKLLFAP
NLLLDRNQGKCVEGMVEIFDMLLATSSRFRMMNLQGEEFVCLKSIILLNS
GVYTFDHIHRVLDKITDTLIHLMAKAGLTLQQQHQRLAQLLLILSHIRHM
SNKGMEHLYSMKCKNVVPLSDLLLEMLDAHL
Ligand information
>5hyr Chain F (length=11) Species:
32630
(synthetic construct) [
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HKKLHRKLQDS
Receptor-Ligand Complex Structure
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PDB
5hyr
Stapled Peptides with gamma-Methylated Hydrocarbon Chains for the Estrogen Receptor/Coactivator Interaction.
Resolution
2.271 Å
Binding residue
(original residue number in PDB)
I358 K362 L372 V376 E380 L539 E542
Binding residue
(residue number reindexed from 1)
I52 K56 L66 V70 E74 L222 E225
Enzymatic activity
Enzyme Commision number
?
External links
PDB
RCSB:5hyr
,
PDBe:5hyr
,
PDBj:5hyr
PDBsum
5hyr
PubMed
26928945
UniProt
P03372
|ESR1_HUMAN Estrogen receptor (Gene Name=ESR1)
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