Structure of PDB 5hyj Chain A Binding Site BS01
Receptor Information
>5hyj Chain A (length=276) Species:
9606
(Homo sapiens) [
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GSHSMRYFFTSVSRPGRGEPRFIAVGYVDDTQFVRFDSDAASQRMEPRAP
WIEQEGPEYWDGETRKVKAHSQTHRVDLGTLRGYYNQSEAGSHTVQRMYG
CDVGSDWRFLRGYHQYAYDGKDYIALKEDLRSWTAADMAAQTTKHKWEAA
HVAEQLRAYLEGTCVEWLRRYLENGKETLQRTDAPKTHMTHHAVSDHEAT
LRCWALSFYPAEITLTWQRDGEDQTQDTELVETRPAGDGTFQKWAAVVVP
SGQEQRYTCHVQHEGLPKPLTLRWEP
Ligand information
>5hyj Chain C (length=10) Species:
9606
(Homo sapiens) [
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AQWGPDPAAA
Receptor-Ligand Complex Structure
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PDB
5hyj
A "hotspot" for autoimmune T cells in type 1 diabetes.
Resolution
3.06 Å
Binding residue
(original residue number in PDB)
Y7 M45 Y59 E63 K66 H70 T73 D77 Y84 R97 Y99 H114 T143 K146 W147 L156 Y159 W167 Y171
Binding residue
(residue number reindexed from 1)
Y7 M45 Y59 E63 K66 H70 T73 D77 Y84 R97 Y99 H114 T143 K146 W147 L156 Y159 W167 Y171
Enzymatic activity
Enzyme Commision number
?
External links
PDB
RCSB:5hyj
,
PDBe:5hyj
,
PDBj:5hyj
PDBsum
5hyj
PubMed
27183386
UniProt
P04439
|HLAA_HUMAN HLA class I histocompatibility antigen, A alpha chain (Gene Name=HLA-A)
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