Structure of PDB 5hq2 Chain A Binding Site BS01

Receptor Information
>5hq2 Chain A (length=99) Species: 8355 (Xenopus laevis) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
KPHRYRPGTVALREIRRYQKSTELLIRKLPFQRLVREIAQDFKTDLRFQS
SAVMALQEASEAYLVALFEDTNLCAIHAKRVTIMPKDIQLARRIRGERA
Ligand information
>5hq2 Chain I (length=73) [Search DNA sequence] [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
tcgtagacagctctagcaccgcttaaacgcacgtacgcgcgtctccaggc
acgtgtcagatatatacatcctg
Receptor-Ligand Complex Structure
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PDB5hq2 Multivalent Interactions by the Set8 Histone Methyltransferase With Its Nucleosome Substrate.
Resolution4.5 Å
Binding residue
(original residue number in PDB)
R40 Y41 R42 R83 F84 Q85 V117 T118
Binding residue
(residue number reindexed from 1)
R4 Y5 R6 R47 F48 Q49 V81 T82
Enzymatic activity
Enzyme Commision number ?
Gene Ontology
Molecular Function
GO:0003677 DNA binding
GO:0005515 protein binding
GO:0030527 structural constituent of chromatin
GO:0046982 protein heterodimerization activity
Cellular Component
GO:0000786 nucleosome
GO:0005634 nucleus
GO:0005654 nucleoplasm
GO:0005694 chromosome

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Molecular Function

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Cellular Component
External links
PDB RCSB:5hq2, PDBe:5hq2, PDBj:5hq2
PDBsum5hq2
PubMed26953260
UniProtP84233|H32_XENLA Histone H3.2

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