Structure of PDB 5hp1 Chain A Binding Site BS01 |
| >5hp1 Chain A (length=553) Species: 11678 (Human immunodeficiency virus type 1 BH10)
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PISPIETVPVKLKPGMDGPKVKQWPLTEEKIKALVEICTEMEKEGKISKI
GPENPYNTPVFAIKKKDSTKWRKLVDFRELNKRTQDFWEVQLGIPHPAGL
KKKKSVTVLDVGDAYFSVPLDEDFRKYTAFTIPSINNETPGIRYQYNVLP
QGWKGSPAIFQSSMTKILEPFKKQNPDIVIYQYMDDLYVGSDLEIGQHRT
KIEELRQHLLRWGLTTPDKKHQKEPPFLWMGYELHPDKWTVQPIVLPEKD
SWTVNDIQKLVGKLNWASQIYPGIKVRQLSKLLRGTKALTEVIPLTEEAE
LELAENREILKEPVHGVYYDPSKDLIAEIQKQGQGQWTYQIYQEPFKNLK
TGKYARMRGAHTNDVKQLTEAVQKITTESIVIWGKTPKFKLPIQKETWET
WWTEYWQATWIPEWEFVNTPPLVKLWYQLEKEPIVGAETFYVDGAANRET
KLGKAGYVTNKGRQKVVPLTNTTNQKTELQAIYLALQDSGLEVNIVTDSQ
YALGIIQAQPDKSESELVNQIIEQLIKKEKVYLAWVPAHKGIGGNEQVDK
LVS |
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| PDB | 5hp1 Conformational States of HIV-1 Reverse Transcriptase for Nucleotide Incorporation vs Pyrophosphorolysis-Binding of Foscarnet. |
| Resolution | 2.9 Å |
Binding residue
(original residue number in PDB) | W24 F61 L74 D76 R78 N81 E89 I94 G152 K154 P157 Y183 D185 D186 M230 G231 N255 Q258 K259 G262 K263 W266 S280 R284 G285 K353 G359 H361 R448 T473 Q475 K476 Q500 Y501 |
Binding residue
(residue number reindexed from 1) | W24 F61 L74 D76 R78 N81 E89 I94 G152 K154 P157 Y183 D185 D186 M230 G231 N255 Q258 K259 G262 K263 W266 S280 R284 G285 K353 G359 H361 R448 T473 Q475 K476 Q500 Y501 |
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