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Receptor Information

>5h9l Chain A (length=154) Species: 13249 (Rhodnius prolixus) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]

VTSIPTGCNALSGKIMSGFDANRFFTGDWYLTHSRDSEVPVRCEKYQTGS
NLQLNFNGKNGDVKCSGSTVSGNQGFYSFQCTTTSGGSFTSYMAVVETDY
ANYALLYRCGLYGSTTPKDNFLLFNRQSSGEIPAGLSTKLNQLELTSLNK
LGCS

Ligand ID

EAH

InChI

InChI=1S/C20H32O3/c1-2-3-4-5-6-7-8-9-10-11-12-13-14-16-19(21)17-15-18-20(22)23/h6-7,9-14,19,21H,2-5,8,15-18H2,1H3,(H,22,23)/b7-6-,10-9-,12-11+,14-13+/t19-/m1/s1

InChIKey

DVGDBDLZYCUGNU-LBIUVHPXSA-N

SMILES

Software	SMILES
CACTVS 3.341	CCCCC\C=C/C/C=C\C=C\C=C\C[C@@H](O)CCCC(O)=O
ACDLabs 10.04	O=C(O)CCCC(O)C/C=C/C=C/C=C\C\C=C/CCCCC
CACTVS 3.341	CCCCCC=CCC=CC=CC=CC[CH](O)CCCC(O)=O
OpenEye OEToolkits 1.5.0	CCCCCC=CCC=CC=CC=CCC(CCCC(=O)O)O
OpenEye OEToolkits 1.5.0	CCCCC\C=C/C\C=C/C=C/C=CC[C@H](CCCC(=O)O)O

Formula

C20 H32 O3

Name

(5S,7E,9E,11Z,14Z)-5-hydroxyicosa-7,9,11,14-tetraenoic acid

PDB chain

5h9l Chain A Residue 201 [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]

Receptor-Ligand Complex Structure

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Structure summary

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PDB	5h9l Structure and Ligand-Binding Mechanism of a Cysteinyl Leukotriene-Binding Protein from a Blood-Feeding Disease Vector.
Resolution	1.37 Å
Binding residue (original residue number in PDB)	F58 F91 S93 M95 R110 N122
Binding residue (residue number reindexed from 1)	F56 F89 S91 M93 R108 N120
Annotation score	1

Enzyme Commision number

	Biological Process
GO:0030682	symbiont-mediated perturbation of host defenses

	Cellular Component
GO:0005576	extracellular region

PDB	RCSB:5h9l, PDBe:5h9l, PDBj:5h9l
PDBsum	5h9l
PubMed	27124118
UniProt	Q7YT09

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Structure of PDB 5h9l Chain A Binding Site BS01