Structure of PDB 5h43 Chain A Binding Site BS01
Receptor Information
>5h43 Chain A (length=428) Species:
9606
(Homo sapiens) [
Search protein sequence
] [
Download receptor structure
] [
Download structure with residue number starting from 1
] [
View receptor structure
]
NQGTVNWSVDDIVKGINSSNVENQLQATQAARKLLSREKQPPIDNIIRAG
LIPKFVSFLGRTDCSPIQFESAWALTNIASGTSEQTKAVVDGGAIPAFIS
LLASPHAHISEQAVWALGNIAGDGSVFRDLVIKYGAVDPLLALLAVPDMS
SLACGYLRNLTWTLSNLCRNKNPAPPIDAVEQILPTLVRLLHHDDPEVLA
DTCWAISYLTDGPNERIGMVVKTGVVPQLVKLLGASELPIVTPALRAIGN
IVTGTDEQTQVVIDAGALAVFPSLLTNPKTNIQKEATWTMSNITAGRQDQ
IQQVVNHGLVPFLVSVLSKADFKTQKEAVWAVTNYTSGGTVEQIVYLVHC
GIIEPLMNLLTAKDTKIILVILDAISNIFQAAEKLGETEKLSIMIEECGG
LDKIEALQNHENESVYKASLSLIEKYFS
Ligand information
>5h43 Chain B (length=10) Species:
9606
(Homo sapiens) [
Search peptide sequence
] [
Download ligand structure
] [
Download structure with residue number starting from 1
] [
View ligand structure
]
RNQKRKHDEI
Receptor-Ligand Complex Structure
Global view
Local view
Structure summary
[
Spin on
] [
Spin off
] [
Reset
]
[
High quality
] [
Low quality
]
[
White background
] [
Black background
]
[
Spin on
] [
Spin off
] [
Reset
]
[
High quality
] [
Low quality
]
[
White background
] [
Black background
]
PDB
5h43
Structural insights into the nuclear import of the histone acetyltransferase males-absent-on-the-first by importin alpha 1
Resolution
2.3 Å
Binding residue
(original residue number in PDB)
R315 V321 T322 D325 T328 K353 E354 W357 N361 A364 G365 E396 W399 N403 S406
Binding residue
(residue number reindexed from 1)
R246 V252 T253 D256 T259 K284 E285 W288 N292 A295 G296 E327 W330 N334 S337
Enzymatic activity
Enzyme Commision number
?
External links
PDB
RCSB:5h43
,
PDBe:5h43
,
PDBj:5h43
PDBsum
5h43
PubMed
28991411
UniProt
P52292
|IMA1_HUMAN Importin subunit alpha-1 (Gene Name=KPNA2)
[
Back to BioLiP
]
