Structure of PDB 5h3u Chain A Binding Site BS01

Receptor Information

>5h3u Chain A (length=670) Species: 9606 (Homo sapiens) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]

QEPRTLPPSPNWYCARCSDAVPGGLFGFAARTSVFLVRVGPGAGESPGTP
PFRVIGELVGHTERVSGFTFSHHPGQYNLCATSSDDGTVKIWDVETKTVV
TEHALHQHTISTLHWSPRVKDLIVSGDEKGVVFCYWFNRNDSQHLFIEPR
TIFCLTCSPHHEDLVAIGYKDGIVVIIDISKKGEVIHRLRGHDDEIHSIA
WCPLPGCYLATGSKDQTIRIWSCSRGRGVMILKLPFLKRVKERLWLTLHW
PSNQPTQLVSSCFGGELLQWDLTQSWRRKYTLFSASGQNHSRIVFNLCPL
QTEDDKQLLLSTSMDRDVKCWDIATLECSWTLPSLGGFAYSLAFSSVDIG
SLAIGVGDGMIRVWNTLSIKNNYDVKNFWQGVKSKVTALCWHPTKEGCLA
FGTDDGKVGLYDTYSNKPPQISSTYHKKTVYTLAWGPPVPPMSLALYSCG
GEGIVLQHNPWKLSGEAFDINKLIRDTNSIKYKLPVHTEISWKADGKIMA
LGNEDGSIEIFQIPNLKLICTIQQHHKLVNTISWHHEHGSQPELSYLMAS
GSNNAVIYVHNLKTVIESSPESPVTITEPYRTLSGHTAKITSVAWSPHHD
GRLVSASYDGTAQVWDALREEPLCNFRGHRGRLLCVAWSPLDPDCIYSGA
DDFCVHKWLTSMQDHSRPPQ

Ligand information

>5h3u Chain C (length=7) [Search RNA sequence] [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]

aauuuuu

.......

Receptor-Ligand Complex Structure

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Structure summary

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PDB	5h3u Structural basis for specific recognition of pre-snRNA by Gemin5
Resolution	2.499 Å
Binding residue (original residue number in PDB)	N13 W14 Y15 R33 R66 R284 R335 R359 G380 F381 Y383 G400 W422 K428 F705
Binding residue (residue number reindexed from 1)	N11 W12 Y13 R31 R64 R243 R292 R316 G337 F338 Y340 G357 W379 K385 F653

Enzymatic activity

Enzyme Commision number

External links

PDB	RCSB:5h3u, PDBe:5h3u, PDBj:5h3u
PDBsum	5h3u
PubMed	27834343
UniProt	Q8TEQ6\|GEMI5_HUMAN Gem-associated protein 5 (Gene Name=GEMIN5)

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