Structure of PDB 5h2x Chain A Binding Site BS01
Receptor Information
>5h2x Chain A (length=418) Species:
559292
(Saccharomyces cerevisiae S288C) [
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ELPQMTQQLNSDDMQEQLSATVKFRQILSREHRPPIDVVIQAGVVPRLVE
FMRENQPEMLQLEAAWALTNIASGTSAQTKVVVDADAVPLFIQLLYTGSV
EVKEQAIWALGNVAGDSTDYRDYVLQCNAMEPILGLFNSNKPSLIRTATW
TLSNLCRGKKPQPDWSVVSQALPTLAKLIYSMDTETLVDACWAISYLSDG
PQEAIQAVIDVRIPKRLVELLSHESTLVQTPALRAVGNIVTGNDLQTQVV
INAGVLPALRLLLSSPKENIKKEACWTISNITAGNTEQIQAVIDANLIPP
LVKLLEVAEYKTKKEACWAISNASSGGLQRPDIIRYLVSQGCIKPLCDLL
EIADNRIIEVTLDALENILKMGEADKEANENADFIEKAGGMEKIFNCQQN
ENDKIYEKAYKIIETYFG
Ligand information
>5h2x Chain B (length=19) Species:
559292
(Saccharomyces cerevisiae S288C) [
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RKHKFDTSTWALPNKRRRI
Receptor-Ligand Complex Structure
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PDB
5h2x
Structures of the Karyopherins Kap121p and Kap60p Bound to the Nuclear Pore-Targeting Domain of the SUMO Protease Ulp1p
Resolution
2.2 Å
Binding residue
(original residue number in PDB)
S116 R117 E118 P121 W153 N157 A159 S160 G161 T162 Q192 W195 N199 G202 D203 W237 N241 R244 K247 D276 V327 G329 K359 E360 W363 N367 E402 W405
Binding residue
(residue number reindexed from 1)
S29 R30 E31 P34 W66 N70 A72 S73 G74 T75 Q105 W108 N112 G115 D116 W150 N154 R157 K160 D189 V240 G242 K272 E273 W276 N280 E315 W318
Enzymatic activity
Enzyme Commision number
?
External links
PDB
RCSB:5h2x
,
PDBe:5h2x
,
PDBj:5h2x
PDBsum
5h2x
PubMed
27939291
UniProt
Q02821
|IMA1_YEAST Importin subunit alpha (Gene Name=SRP1)
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