Structure of PDB 5gtr Chain A Binding Site BS01

Receptor Information
>5gtr Chain A (length=236) Species: 9606 (Homo sapiens) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
SLALSLTADQMVSALLDAEPPILYSESEASMMGLLTNLADRELVHMINWA
KRVPGFVDLTLHDQVHLLECAWLEILMIGLVWRSMEHPGKLLFAPNLLLD
RNQGKCVEGMVEIFDMLLATSSRFRMMNLQGEEFVCLKSIILLNSGVYTF
LSSTLKSLEEKDHIHRVLDKITDTLIHLMAKAGLTLQQQHQRLAQLLLIL
SHIRHMSNKGMEHLYSMKCKNVVPLYDLLLEMLDAH
Ligand information
Receptor-Ligand Complex Structure
Global viewLocal viewStructure summary

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PDB5gtr Structural Basis of Inhibition of ER alpha-Coactivator Interaction by High-Affinity N-Terminus Isoaspartic Acid Tethered Helical Peptides
Resolution2.804 Å
Binding residue
(original residue number in PDB)
V355 I358 K362 L372 V376 E542 M543
Binding residue
(residue number reindexed from 1)
V44 I47 K51 L61 V65 E231 M232
Enzymatic activity
Enzyme Commision number ?
External links
PDB RCSB:5gtr, PDBe:5gtr, PDBj:5gtr
PDBsum5gtr
PubMed29045135
UniProtP03372|ESR1_HUMAN Estrogen receptor (Gene Name=ESR1)

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