Structure of PDB 5grd Chain A Binding Site BS01
Receptor Information
>5grd Chain A (length=274) Species:
9606
(Homo sapiens) [
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GSHSMRYFYTSVSRPGRGEPRFIAVGYVDDTQFVRFDSDAASQRMEPRAP
WIEQEGPEYWDQETRNVKAQSQTDRVDLGTLRGYYNQSEDGSHTIQIMYG
CDVGPDGRFLRGYRQDAYDGKDYIALNEDLRSWTAADMAAQITKRKWEAA
HAAEQQRAYLEGRCVEWLRRYLENGKETLQRTDPPKTHMTHHPISDHEAT
LRCWALGFYPAEITLTWQRDGEDQTQDTELVETRPAGDGTFQKWAAVVVP
SGEEQRYTCHVQHEGLPKPLTLRW
Ligand information
>5grd Chain C (length=10) Species:
32630
(synthetic construct) [
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SSCSSCPLSK
Receptor-Ligand Complex Structure
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PDB
5grd
Dual non-contiguous peptide occupancy of HLA class I evoke antiviral human CD8 T cell response and form neo-epitopes with self-antigens
Resolution
1.8 Å
Binding residue
(original residue number in PDB)
Y7 E63 N66 D77 Y84 Y99 D116 T143 K146 W147 Q155 Q156 Y159 R163 W167 Y171
Binding residue
(residue number reindexed from 1)
Y7 E63 N66 D77 Y84 Y99 D116 T143 K146 W147 Q155 Q156 Y159 R163 W167 Y171
Enzymatic activity
Enzyme Commision number
?
External links
PDB
RCSB:5grd
,
PDBe:5grd
,
PDBj:5grd
PDBsum
5grd
PubMed
28698575
UniProt
P04439
|HLAA_HUMAN HLA class I histocompatibility antigen, A alpha chain (Gene Name=HLA-A)
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