Structure of PDB 5gr8 Chain A Binding Site BS01

Receptor Information
>5gr8 Chain A (length=710) Species: 3702 (Arabidopsis thaliana) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
LNSDGLTLLSLLKHLDRVPPQVTSTWKINASEATPCNWFGITCDDSKNVA
SLNFTRSRVSGQLGPEIGELKSLQILDLSTNNFSGTIPSTLGNCTKLATL
DLSENGFSDKIPDTLDSLKRLEVLYLYINFLTGELPESLFRIPKLQVLYL
DYNNLTGPIPQSIGDAKELVELSMYANQFSGNIPESIGNSSSLQILYLHR
NKLVGSLPESLNLLGNLTTLFVGNNSLQGPVRFGSPNCKNLLTLDLSYNE
FEGGVPPALGNCSSLDALVIVSGNLSGTIPSSLGMLKNLTILNLSENRLS
GSIPAELGNCSSLNLLKLNDNQLVGGIPSALGKLRKLESLELFENRFSGE
IPIEIWKSQSLTQLLVYQNNLTGELPVEMTEMKKLKIATLFNNSFYGAIP
PGLGVNSSLEEVDFIGNKLTGEIPPNLCHGRKLRILNLGSNLLHGTIPAS
IGHCKTIRRFILRENNLSGLLPEFSQDHSLSFLDFNSNNFEGPIPGSLGS
CKNLSSINLSRNRFTGQIPPQLGNLQNLGYMNLSRNLLEGSLPAQLSNCV
SLERFDVGFNSLNGSVPSNFSNWKGLTTLVLSENRFSGGIPQFLPELKKL
STLQIARNAFGGEIPSSIGLIEDLIYDLDLSGNGLTGEIPAKLGDLIKLT
RLNISNNNLTGSLSVLKGLTSLLHVDVSNNQFTGPIPDNLEGQLLSEPSS
FSGNPNLCIP
Ligand information
>5gr8 Chain J (length=17) Species: 3702 (Arabidopsis thaliana) [Search peptide sequence] [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
KQRGKEKVSSGRPGQHN
Receptor-Ligand Complex Structure
Global viewLocal viewStructure summary

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PDB5gr8 Structural basis for recognition of an endogenous peptide by the plant receptor kinase PEPR1
Resolution2.587 Å
Binding residue
(original residue number in PDB)		Y153 Y155 Y177 D179 E199 Y203 Y225 H227 F249 D273 S275 V297 N321 K345 D348 F371 Y395 F419 D441 I443 I463 N465 R487 I489
Binding residue
(residue number reindexed from 1)		Y125 Y127 Y149 D151 E171 Y175 Y197 H199 F221 D245 S247 V269 N293 K317 D320 F343 Y367 F391 D413 I415 I435 N437 R459 I461
Enzymatic activity
Enzyme Commision number 2.7.11.1: non-specific serine/threonine protein kinase.
External links
PDB RCSB:5gr8, PDBe:5gr8, PDBj:5gr8
PDBsum5gr8
PubMed25475059
UniProtQ9SSL9|PEPR1_ARATH Leucine-rich repeat receptor-like protein kinase PEPR1 (Gene Name=PEPR1)

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