Structure of PDB 5gke Chain A Binding Site BS01

Receptor Information
>5gke Chain A (length=239) Species: 69014 (Thermococcus kodakarensis KOD1) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
SKDKVTVITSPSTEELVSLVNSALLEEAMLTIFARCKVHYDGRAKSELGS
GDRVIIVKPDGSFLIHQSKKREPVNWQPPGSRVRLELRENPVLVSIRRKP
RETLEVELEEVYMVSVFRAEDYEELALTGSEAEMAELIFENPEVIEPGFK
PLFREKAIGTGIVAVLGRDSDGNIVVLELKRRRAELHAVRQLKSYVEILR
EEYGDKVRGILVAPSLTSGAKRLLEKEGLEFRKLEPPKR
Ligand information
Receptor-Ligand Complex Structure
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PDB5gke Structure of the EndoMS-DNA Complex as Mismatch Restriction Endonuclease
Resolution2.4 Å
Binding residue
(original residue number in PDB)		K71 R72 E73 K100 L128 E132 G162 I163 K181 R182 R183 Q192 Y196
Binding residue
(residue number reindexed from 1)		K70 R71 E72 K99 L127 E131 G161 I162 K180 R181 R182 Q191 Y195
Binding affinityPDBbind-CN: Kd=3.4nM
Enzymatic activity
Enzyme Commision number 3.1.-.-
Gene Ontology
Molecular Function
GO:0000014 single-stranded DNA endodeoxyribonuclease activity
GO:0003676 nucleic acid binding
GO:0003677 DNA binding
GO:0004519 endonuclease activity
Biological Process
GO:0006259 DNA metabolic process
Cellular Component
GO:0005737 cytoplasm

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Cellular Component
External links
PDB RCSB:5gke, PDBe:5gke, PDBj:5gke
PDBsum5gke
PubMed27773688
UniProtQ5JER9|NUCS_THEKO Endonuclease NucS (Gene Name=nucS)

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